Research and Reports in Gynecology and Obstetrics

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-7360-538437

Research Article - Research and Reports in Gynecology and Obstetrics (2017) Volume 0, Issue 0

A comparison of spot urine protein-creatinine ratio with 24 hour urine protein excretion for prediction of proteinuria in preeclampsia.

Objective: To examine the correlation between spot urine PCR and 24-hour urine protein excretion in patients being evaluated for preeclampsia. Population or sample: 98 pregnant women with suspected preeclampsia and a gestational age more than 20 weeks.

Methods: A random urine sample was collected immediately before or after the 24-hour urine collection. The protein creatinine ratio was calculated by dividing the urinary protein concentration by the urinary creatinine concentration, and the correlation with the 24-hour urine protein excretion was assessed.

Results: PCR at a cut-off value of 0.02 g/mmol (0.18 g/g) had sensitivity and a specificity of 97.6% and 44% respectively in predicting proteinuria of 300 mg/24 hour. The positive predictive value was 58%, and negative predictive value was 96%.

Conclusion: There is strong correlation between spot PCR and 24-hour urine protein collection. PCR could be a reasonable alternative to clinicians in order to reduce their dependence on the 24-hour urine collection.

Author(s): Nedaa Obeid*, Ruth O'Kelly, Feras Abu Saadeh, Vivion Crowley, Sean Daly

Abstract Full Text PDF

Get the App