Asian Journal of Biomedical and Pharmaceutical Sciences

Asian Journal of Biomedical and Pharmaceutical Sciences 44 7897 074717

Pharmacovigilance Scholarly Journal

Pharmacovigilance  which is  is understood to be,drug safety control, is that the pharmacological science pertaining to those gather, discovery, evaluation, monitoring, and prevention of adverse reactions ofpharmaceutical products. Therapeutic strategies required to medicine in their marketing. is that the sole branch of mainstream medicine that follows the Hippocratic approach, overcome this excessive inflammatory response Aging, smoking/vaping results in severe disease outcome and mortality amongst COVID-19 patients. SARS-CoV-2 with a membrane spike glycoprotein furin along with its receptor ACE2 and TMPRSS2 protease are increased by smoking/vaping in lung epithelium rendering viral entry and augmented infection. This results in a ‘cytokine storm’ involving excessive production of pro-inflammatory cytokines/chemokines.

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