Journal of Neurology and Neurorehabilitation Research

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Journal of Neurology and Neurorehabilitation Research 44 7897 074717

Inflammatory Polyneuropathies

Chronic inflammatory demyelinating polyneuropathy (or polyradiculoneuropathy) is careful autoimmune disorder finishing myelin, the protective cover of the nerves. Typical initial symptoms are "tingling" (sort of electrified vibration or paresthesia) or numbness in the extremities, frequent (night) leg cramps, loss of reflexes (in knees), muscle fasciculations, "vibration" feelings, loss of balance, over-all muscle cramping, and nerve pain. CIDP is tremendously rare but under-recognized and under-treated due to its heterogeneous presentation (both clinical and electrophysiological) and the limitations of clinical, serologic, and electrophysiologic diagnostic criteria. Despite these limitations, early diagnosis and action are favored in preventing irreversible axonal loss and improving functional recovery.

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