Journal of Physical Therapy and Sports Medicine

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Journal of Physical Therapy and Sports Medicine 44 7897 074717

Diffuse Correlation Spectroscopy

DCS provides a transportable, noninvasive, and cheap alternative for microvascular blood flow measurements and has been validated against other standards, including power spectral Doppler ultrasound, Doppler ultrasound, laser Doppler flowmetry, Xenon computerized tomography, fluorescent microsphere flow measurement and ASL-MRI. The DCS technology has been extensively introduced into various tissues, including brain, tumor and striated muscle. The applications of DCS in brain and tumor are previously reviewed. Interested readers are encouraged to read these publications for details. This review paper will specialize in introducing some recent progress of DCS within the study of skeletal muscles. The key components of a DCS flow-meter include an extended coherence length laser at NIR range, a single-photon-counting avalanche photodiode (APD) detector and an autocorrelator board. Other components, like source/detector fibers, computer, and A/D board, are wont to couple light in/out of tissue or control/record optical data. For tissue blood flow measurement, the laser placed on the tissue surface (e.g., skin) launches long-coherence NIR light into the tissue via a multiple-mode source fiber, and therefore the light transported/ scattered through the tissue was collected by a single-mode (or a fewmode) detector fiber placed millimeters to centimeters far away from the source fiber. The detected light is then delivered via the detector fiber to APD detector, where the count of photons per unit time (i.e., light intensity) is recorded. 

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