Allied Journal of Medical Research

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Allied Journal of Medical Research 44 7897 074717

Articles On Thalassemia

Thalassemia is an genetic blood disorder characterized by less oxygen-carrying protein (haemoglobin) and fewer red blood cells within the body than normal.

Symptoms include weakness, fatigue, paleness and slow growth.

Mild forms might not need treatment. Severe forms could need blood transfusions or a donor stem-cell transplant. thalassemia occurs once there's a defect in a very gene that helps control production of 1 of those proteins.

There are 2 main varieties of thalassemia:

Alpha thalassemia occurs once a gene or genes related to the alpha {globin| hematohiston |haematohiston| simple macromolecule} protein are missing or modified (mutated).

Beta thalassemia occurs once similar gene defects have an effect on production of the beta {globin|hematohiston|haematohiston|simple protein} protein.

Alpha thalassemias occur most frequently in individuals from Southeast Asia, the middle East, China, and in those of African descent.

Beta thalassemias occur most frequently in individuals of Mediterranean origin. To a lesser extent, Chinese, different Asians, and African Americans will be affected.

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