+44-7360-538437The combined use of fat graft enriched with stromal vascular fraction cells and platelet-rich plasma in the treatment of breast soft tissue defect
Joint Event on 2nd International Conference on Tissue Science and Molecular Biology, Stem Cells & Separation Techniques
June 06-07, 2019 | London, UK
Pietro Gentile
University of Rome Tor Vergata, Italy
Posters & Accepted Abstracts : Biomed Res
Abstract:
The use of autologous fat grafting is ideal in breast reconstruction. However, published data on long-term outcomes and instrumental results of fat grafting to the breast are lacking. The purpose of this study was to review the authorsâ experience of fat grafting, evaluating the effects related to the use of enhanced stromal vascular fraction (e-SVF) and fat grafting with platelet-rich plasma (PRP) in the maintenance of fat volume in breast reconstruction, comparing the results with a control group. Twenty-three patients aged 19â60 years affected by breast soft tissue defects were analyzed at the Plastic and Reconstructive Department of the University of Rome Tor Vergata. 10 patients were treated with SVF-enhanced autologous fat grafts and 13 patients were treated with fat grafting mixed with plateletrich plasma. The patients in the control group (n=10) were treated with centrifuged fat grafting injection according to Colemanâs procedure. The patients treated with SVFenhanced autologous fat grafts showed a 63% maintenance of the contour restoring and of three-dimensional volume after 1 year compared with the patients of the control group treated with centrifuged fat graft, who showed a 39% maintenance. In those patients who were treated with fat grafting and PRP, we observed a 69% maintenance of contour restoring and of three-dimensional volume after 1 year. As reported, the use of either e-SVF or PRP mixed with fat grafting produced an improvement in maintenance of breast volume in patients affected by breast soft tissue defect.
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