MACULAR AND RETINAL NERVE FIBER LAYER ANALYSIS BY OPTICAL COHERENCE TOMOGRAPHY IN NORMAL CHILDREN
2nd GLOBAL OPHTHALMOLOGY SUMMIT 2019
March 27-28, 2019 | Amsterdam, Netherlands
Asmaa N Ali, Rania K Farag, Tarek A Abd El Wahab and Asaad A Ghanem
Mansoura Ophthalmology Center, Egypt
Posters & Accepted Abstracts : Ophthalmol Case Rep
Abstract:
This study aims to evaluate macular and peripapillary retinal nerve fiber layer measurements in normal children
and their correlation with age, gender, laterality, refraction and axial length
Methods: This was an observational cross sectional study among 100 eyes of 50 child (25 boys, 25 girls) aged
between 6 and 17 years. After detailed eye examination and axial length measurements, the children were
scanned using swept source optical coherence tomography (3D DRI OCT Triton [plus], Topcon Corporation,
Tokyo, Japan) to measure macular thickness, macular volume, peripapillary RNFL thickness and optic disc parameters.
Results: Both eyes of fifty child were included in the study. Mean age was 10.96 ± 2.75 years, average spherical
equivalent refraction (SE) was 0.78±1.65 (−4.50 to +5.00) diopters and average axial length was 22.87
± 0.90 (20.99 to 24.67) mm. Average macular thickness was 276.41±17.8 μm, central macular thickness was
225.26±20.79 μm, mean macular volume was 7.84±0.48 mm3 and mean peripapillary RNFL thickness was
111.26±20.46 μm. Axial length showed positive correlation with age unlike negative correlation with spherical
equivalent. It also showed negative correlation with mean average RNFL thickness. Most of the parafoveal
region quadrants correlated positively with age unlike RNFL measurements that correlated negatively. Central
macular thickness values were significantly higher in males (p=0.001) but there was no difference between
male and female as regard RNFL thickness. Spherical equivalent didn’t show significant effect on studied parameters.
Concerning the side of the eye, it had no statistically significant difference between both eyes but
good correlation.
Conclusion: Normative paediatric SS-OCT data might facilitate use of SS-OCT for assessing childhood ophthalmic
diseases. This study provides a paediatric normative database of SS-OCT peripapillary RNFL and macular
data.
Biography:
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