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Lab Allergy Testing: Assessing Frequency of Food and Environmental Allergens in Pakistani Population
Joint Event on Global Experts Meeting on STD-AIDS and Infectious Diseases & 12th International Conference on Allergy, Immunology and Rheumatology
November 21-22, 2019 | Singapore
Ghani F
Aga Khan University Hospital, Pakistan
Scientific Tracks Abstracts : J Infectious Disease Med Microbiol
Abstract:
Food and environmental allergies are common in childhood
and adults. It has been suggested that the magnitude of an
allergen specific IgE result can improve diagnostic usefulness,
but this has been addressed in only a few tertiary challengebased
studies. This study aims to assess the frequency of
food and environmental allergens in our population. The
study population consisted of 88 individuals (male: 47
and female: 41). The study was conducted in the clinical
laboratory, department of pathology and microbiology,
Aga Khan University Hospital from May 2009, till May
2010. Sera of patients positive for total IgE were tested for
allergen specific IgE levels by immulite 2000, 3gAllergyTM.
There were a total of 27 allergens tested on 88 individuals
having positive total IgE. We have analyzed the data on two
cutoffs of allergen specific IgE i.e. moderate (0.7-3.49 kU/L)
and high (3.5-17.49 kU/L). The results suggest that in moderate
reactivity the most common allergen from environmental
panel was dog epithelium (46.6%), mites (33%), cockroach
(17%) and from food panel was egg white (23.9%), milk
(22.7%)and soybean (13.6%) but in high reactivity the
commonest allergen was mites (6.8%),cockroach (4.5%),cat
dander epithelium (3.4%),D.farinae (3.4%), molds (3.4%) and
weeds (3.4%) from environmental panel and egg white (2.3%),
peanuts (2.3%) and shrimps (2.3%) from food panel. At very
high reactivity (>52.50 kU/L) most common environmental
allergens seen were mites (2.3%), cat dander epithelium
(1.1%) and common food allergens were shrimps (1.1%) and
peanuts (1.1%). Results generated from our study showed
that there is high frequency of environmental and food
allergies in our patients and total IgE levels are correlating
with specific IgE levels.
Biography:
Farooq Ghani did his MBBS from Karachi followed by training in Pathology
at Boston University Medical Center USA. He did his fellowship in Pathology
and Laboratory Medicine in Boston plus a PhD in Pathology from Boston
University. He is a Diplomate American Board of Clinical Chemistry and
Fellow of National Academy of Clinical Biochemistry USA. Dr Ghani has spent
most of his professional career in United States. He has held faculty and
consultant positions at Boston University Medical Center, Hartford Hospital
Connecticut, New York Medical College at Westchester Medical Center New
York and was Director at Bayer Healthcare in Tarrytown New York. Upon his
return to Pakistan he joined Aga Khan University in 2007. He is currently
the Service Chief, Department of Pathology & Laboratory Medicine at The
Aga Khan University Hospital. He has published extensively in reputable
peer reviewed journals and has many book chapters to his credit.
E-mail: farooq.ghani@aku.edu
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