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Fatal case of non-culturable Meningitis with Pulmonary Embolism
Joint Event on International Conference on Pathology and Infectious Diseases & 3rd International Conference on Pathology and Oncology Research
November 11-12, 2019 | Singapore
Pisespong Patamasucon
Rocky Mountain Hospital for Children, USA
Keynote : J Infectious Disease Med Microbiol
Abstract:
A 16 year old female presented to Emergency Department
with complaint of a severe headache for 3 days, vomiting,
and a low grade fever. She had previously been diagnosed 3
weeks earlier with Epstein - Barr virus and was currently taking
oral prednisolone. The work up in the ED found an increase
intracranial pressure up to 50cm H2O with CSF WBC of 3661
with 96% PMN, very low glucose at < 5 mg/dl and high protein
at 429 mg/dl which is compatible with bacterial meningitis. The
chest x-ray showed suspicion of pulmonary emboli. Antibiotics
initially given in the Emergency room were ceftriaxone and
vancomycin. She was also intubated and put on respiratory
support. Metronidazole was added on day 2 of admission.
The blood, urine, and CSF all showed no growth on culture
and the meningo-encephalitis panel PCR was negative for
usual bacterial viruses and fungal pathogens. A bacterial PCR
collected from the bronchial lavage was sent out to find the
actual causative agent. A subsequent CT scan with contrast of
the neck found an internal jugular vein thrombosis. After six
days of admission, she developed severe brain swelling and
herniated, no further intervention was done as requested by
her mother and she expired on that day.
Biography:
Pisespong Patamasucon, M.D. is the Director of Pediatric Infectious Diseases at Rocky Mountain Hospital for Children. Previously the Director of Pediatric Infectious Diseases and Professor of Pediatrics at the University of Nevada School of Medicine. He studied at the Chiang Mai University in Thailand before completing pediatric residencies at the Children's Hospital in Bangkok, Thailand, and Georgetown University in Washington D.C. Following his Georgetown residency, he has completed a fellowship at the University of Texas South Western Medical School in Dallas. Prior to his roles at the University of Nevada School of Medicine, he was the Director of Pediatric Infectious Diseases and Director of the International Health Program at the University of Tennessee Medical Center at Knoxville. While at the University of Tennessee, Dr. Patamasucon established and oversaw an exchange program between the university's medical program and schools and teaching hospitals in Thailand.
E-mail: Pisespong.patamasucon@hcahealthcare.com
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