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Contact sensitization in children aged 10 years and below: Trends in allergens in a 10 year retrospective study of 337 tested children in a single dermatology centre
Joint Event on 2nd Global Summit on Dermatology and Cosmetology & 3rd International Conference on Wound Care, Tissue Repair and Regenerative Medicine
September 09-10, 2019 | Edinburgh, Scotland
Hrvatin Stancic Bor
University Medical Centre Ljubljana, Slovenia
Posters & Accepted Abstracts : Dermatol Res Skin Care
Abstract:
Introduction and objectives: Contact sensitization can be a
cause of eczema in children. It is known that causative agents
change with time. The aim of our study was to evaluate the
results of patch testing in children aged 10 and below with
suspected allergic contact dermatitis(ACD), for the most
common allergens and trends in allergens.
Materials and methods: We retrospectively evaluated
the results of 337 patch tested children 10 years of age
or younger, tested with a standard series of 23 allergens
between 1.1.2005 and 31.12.2014 at the Dermatology
Department, University Medical Centre Ljubljana. Out of 337
children there were 145(43%) boys(M) and 192(57%) girls(F),
aged between 2 and 10 years(mean 7.02). Out of all tested
individuals, the three most frequent positive patch test(PPT)
reactions were to nickel sulphate(12,5%), fragrance mix(8,9%)
and cobalt(7,4%). We evaluated the first 5 years and second
5 years separately and examined each tested allergen for
emerging trends. In the first 5 years(2005-2009 G1) there
were 117 patients 42.7%(M), 57,3%(F) and in the second
group(2010-2014 G2) there were 220 patients 43.2%(M),
56.8%(F). In G1 there were 44.4% and in G2 37.3% PPTs to at
least one allergen.
Results and conclusions: Like some other studies we did not
find a correlation between sex and a PPT(p=0.55) and nickel
remained the most common allergen in both groups(G1:11%,
G2:13%). By comparing the two groups we found an increase
in the incidence of PPTs in cobalt(G1:5%, G2:9%), peru
balsam(G1:1%, G2:4%), fragrance mix(G1:6%, G2:10%)
and a decrease of PPT in para-phenylenediamine(G1:8%,
G2:4%), neomycin(G1:8%, G2:5%), lanolin(G1:7%, G2:4%)
and sesquiterpene lactone mix(G1:5%, G2:1%). We found
a statistically significant decrease in PPT to sesquiterpene
lactone mix(p=0.015). It may be postulated that the decrease
in sesquiterpene lactone mix may be due to a decreased time
spent outdoors in this age group.
Biography:
Hrvatin Stancic Bor has received his medical degree at the age of 24 from the University of Ljubljana, Medical Faculty. During and after his studies he has attended several international elective interniships at Imperial College London, at the University of Padua, at the University of Bologna, at Memorial Hermann–Texas Medical Center and at Dr. M Djamil Public hospital, Padang Indonesia. He has attended a number of congresses in the field of Dermatology and furthermore organized and presented at Melanoma: from A to E congress for students and residents.
E-mail: bor.h.st@gmail.com
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