+1 (629)348-3199Association between HbA1C levels and pregnancy outcome in diabetic pregnancies
27th International Conference on Diabetes and Endocrinology
May 16-17, 2019 | Prague, Czech Republic
Adel Taha Abu Heija
Mutah University, Jordan
Posters & Accepted Abstracts : J Diabetol
Abstract:
Objective: To study the association between HbA1C levels and
maternal & perinatal outcome, in pregnancies complicated
with diabetes mellitus.
Method: It is an observational retrospective study. In this
study we reviewed all singleton pregnant women with any
type of diabetes who gave birth in Sultan Qaboos University
Hospital, Muscat, Oman between (2013 - 2015). During the
study period, there were 9,358 deliveries, of whom 966
pregnancies complicated by diabetes mellitus (DM) 10.29%.
We excluded twin and triplet gestations complicated by DM
(N=19), so the study group comprised of 947 (10.1%). In this
study, HbA1C was performed in each trimester and results
were considered abnormally high when it exceeds 6%.
Results: In this study,16% of women studied were aged under
25 years, 66% aged between 25-35 years and 18% aged more
than 35 years. Regarding body mass index (BMI) of the study
population, 64% had BMI. 29 kg/m2, 25% had BMI between
25-29 kg/m2 and 11% of women had BMI under 25 kg/m2.
It is shown that only 1.2% of women had type 1 DM, 8.2%
had pre-gestational diabetes mellitus (PGDM) and 90.6% had
gestational diabetes mellitus (GDM). Majority of women with
GDM, blood sugar was controlled with diet alone (71.5%)
and the rest were controlled by Insulin (19.1%). Macrosomia
was observed only in 0.48% of all deliveries during the study
period while in the study group this was observed in 4.7% of
women nearly 10 times. While caesarean delivery increased
from 22% during the study period to 26.6% in the study group
(P<0.001). Cesarean section rate of 26.6% was significantly
correlated with mean HbA1C levels in 2nd and 3rd trimesters
(p<0.001). There were 9 stillbirth and 5 IUFDs, 7 stillbirths
and 4 IUFDs had HbA1C>8%. All neonatal complications have
positive correlation with HbA1C in 2nd and 3rd trimesters.
Conclusions: Starting from a first-trimester, HbA1C level >6%,
there is associated with adverse pregnancy outcome.
Biography:
E-mail:
abuheija2008@hotmail.comPDF HTML