+44 1400 53005553 Newborns with Hypoxic Ischemic Encephalopathy treated with Hypothermia therapy using Neonatal Laminar Flow Unit
Joint Event on 12th International Conference on Pediatrics Health Care & International Conference and Medicare Expo on Primary Healthcare
August 16-17, 2018 | Paris, France
Jose M R Perez
Casa de Saude de Guarulhos and Stella Maris Hospital-Guarulhos-SP, Brazil
Posters & Accepted Abstracts : Curr Pediatr Res
Abstract:
Aim: The aim this trial was observational clinical the newborns with diagnosis of Hypoxic Ischemic Encephalopathy treated with hypothermia therapy in use of the Neonatal Laminar flow unit1. Methods: We involved 53 newborns in this trial, all born in the hospital itself, newborns at up to 35 weeks of gestation, with up to 6 hours of life. Total body cooling was achieved using the neonatal laminar flow unit for 72 hours, with continuous rectal temperature servo control, isolation and humidification. Outcome measures were cerebral palsy, a Bayley II Mental Development Index score <70, hearing loss or blindness. We compared findings with our previously published studies2 and two meta-analyses3,4. Results: We included 53 newborn infants (73% male) with a birthweight of 3.562± 1548 g and gestational age of 38 ±3.4 weeks. We have used to categorize the diagnosis of the Hypoxic Ischemic Encephalopathy, the Siben Neurologic Score 5 associated the Sarnat Score6; the most of the newborns( 73%) had Siben’s score three points or more to serious HIE confirmed by Sarnat Score and 27% had Siben’s score three points or more to moderate HIE confirmed by Sarnat Score. Total body cooling (33–34°C) was achieved in 75 minutes and maintained with servo control. At 18–24 months of age, five of the 38 survivors were diagnosed with cerebral palsy, two was diagnosed with blindness and one with impaired hearing. Conclusion: The use of the Neonatal laminar flow unit to supply total body hypothermia therapy in newborns with HIE was effective and our results were similar our previously trial and two meta-analyses.
Biography:
E-mail:
joseperezneo@gmail.comPDF HTML