Opinion Article - Journal of Molecular Oncology Research (2023) Volume 7, Issue 4
Treatment and Prevention of Skin Cancer Using Nanoparticles as a Therapeutic Delivery System.
Eliana Karczewski *
Department of Health Sciences, University Fernando Pessoa, Porto, Portugal
- *Corresponding Author:
- Eliana Karczewski
Department of Health Sciences
University Fernando Pessoa
Received:27-Jun-2023, Manuscript No. AAMOR-23-103551; Editor assigned:29-Jun-2023, PreQC No. AAMOR-23-103551 (PQ); Reviewed:12-July-2023, QC No. AAMOR-23-103551; Revised:17-July-2023, Manuscript No. AAMOR-23-103551 (R); Published:24-July-2023, DOI:10.35841/ aamor-7.4.186
Skin cancer is one of the most common types of cancer worldwide, and it is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. However, many cases of skin cancer can be prevented or minimized through proactive measures and adopting healthy sun protection habits. Skin cancer prevention aims to reduce the risk factors associated with the development of skin cancer and promote behaviors that protect the skin from harmful UV radiation. Nanoparticles are small particles with sizes going from 1 to 100 nanometers. Due to their small size, nanoparticles exhibit unique properties that make them attractive for biomedical applications. In the context of skin cancer, nanoparticles can be designed and engineered to carry and deliver therapeutic agents directly to the tumor site, bypassing healthy skin cells and minimizing systemic side effects .
The utilization of nanoparticles as a therapeutic delivery system for skin cancer offers several advantages. Firstly, nanoparticles can be modified to enhance their stability, biocompatibility, and drug-loading capacity, ensuring optimal drug delivery. Surface modifications can also enable active targeting of specific cancer cells or tissues, improving treatment efficacy while reducing off-target effects. Furthermore, nanoparticles can protect encapsulated drugs from degradation or premature release, ensuring sustained and controlled drug release at the tumor site. This controlled release allows for prolonged exposure of cancer cells to the therapeutic agents, maximizing their effectiveness in killing or inhibiting tumor growth .
While the field of nanoparticle-based therapeutics for skin cancer is still evolving, preclinical studies and early-phase clinical trials have shown promising results. However, challenges remain in terms of optimizing nanoparticle formulations, ensuring their safety, and scaling up production for wider clinical use .
Effective skin cancer prevention strategies involve a combination of education, awareness, and practical measures to minimize exposure to UV radiation. By taking preventive steps, individuals can significantly reduce their risk of developing skin cancer. Here are some key elements of skin cancer prevention
Sun Protection Education
Raising awareness about the harmful effects of UV radiation and promoting sun-safe behaviors is crucial. Educating individuals about the risk factors, signs, and symptoms of skin cancer can help them make informed decisions and take appropriate precautions
Applying broad-spectrum sunscreen with a Sun Protection Factor (SPF) of 30 or higher is an essential component of sun protection. Sunscreen should be applied generously and re-applied every two hours, especially during prolonged sun exposure or after swimming or sweating. Protective Clothing Wearing protective clothing, such as wide-brimmed hats, long-sleeved shirts, and long pants, can shield the skin from direct sunlight. Opting for tightly woven, loose fitting clothing with a UPF (Ultraviolet Protection Factor) rating can provide extra sun protection
Regular Skin Examinations
Conducting regular self-examinations of the skin can help detect any changes, such as new moles or suspicious growths. Seeking professional medical advice for any concerning skin abnormalities is essential for early detection and prompt treatment, if needed. By implementing these preventive measures, individuals can significantly reduce their risk of developing skin cancer. Remember, prevention is key, and proactive sun protection habits can help safeguard the skin from the harmful effects .
The utilization of nanoparticles as a therapeutic delivery system for the treatment and prevention of skin cancer holds significant promise in advancing the field of oncology. By harnessing the unique properties of nanoparticles, researchers have been able to develop targeted and efficient drug delivery systems, enhancing treatment efficacy while minimizing systemic side effects. Nanoparticles hold immense potential in the fight against skin cancer. Their ability to deliver therapeutic agents directly to the affected cells, their controlled drug release capabilities, and their potential for preventive applications make them a promising avenue for improving skin cancer treatment outcomes and reducing its incidence .
- Sinclair C, Foley P. Skin cancer prevention in australia. Br. J. Dermatol. 2009;161(s3):116-23.
- Buller DB, Borland R. Skin cancer prevention for children: A critical review. Health Educ Behav. 1999;26(3):317-43.
- Gordon LG, Rowell D. Health system costs of skin cancer and cost effectiveness of skin cancer prevention and screening. Eur. J. Cancer Prev. 2015;24(2):141-9.
- Seebode C, Lehmann J, Emmert S. Photocarcinogenesis and skin cancer prevention strategies. Anticancer research. 2016 Mar 1;36(3):1371-8.
- Shih ST, Carter R, Sinclair C, et al. Economic evaluation of skin cancer prevention in australia. Prev Med. 2009;49(5):449-53.