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Perspective - Biology & Medicine Case Reports (2023) Volume 7, Issue 1

The role of neurotransmitters in brain function and communication

Lisa Christine*

Department of Pharmacology, Vanderbilt University, Nashville, USA

*Corresponding Author:
Lisa Christine
Department of Pharmacology
Vanderbilt University, Nashville, USA

Received: 04-Jan-2023, Manuscript No. AABMCR- 23-88888; Editor assigned: 06-Jan-2023, Pre QC No. AABMCR-23-88888 (PQ); Reviewed: 20-Jan-2023, QC No. AABMCR-23-88888; Revised: 22-Jan-2023, Manuscript No. AABMCR 23-88888 (R); Published: 30-Jan-2023, DOI: 10.35841/aabmcr-7.1.133

Citation: Christine Lisa. The role of neurotransmitters in brain function and communication. Biol Med Case Rep. 2023;7(1):133

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The brain is an incredibly complex organ that relies on a variety of chemical signals, known as neurotransmitters, to communicate and regulate different functions within the body. In order to understand the role of neurotransmitters in brain function and communication, it is important to first understand what neurotransmitters are and how they work.


Efficacy, Effectiveness, Tactics, Health care.


Neurotransmitters are chemicals that are produced and released by nerve cells, also known as neurons, in the brain. They act as messengers that transmit signals from one neuron to another, allowing the brain to communicate with other parts of the body. When a neurotransmitter is released from one neuron, it crosses a small gap called a synapse and binds to a receptor on the next neuron. This binding trigger a series of events that either excite or inhibit the next neuron, depending on the type of neurotransmitter and receptor involved [1].

Neurotransmitters are located in a part of the neuron called the axon terminal. They’re stored within thin-walled sacs called synaptic vesicles. Each vesicle can contain thousands of neurotransmitter molecules [2].

As a message or signal travels along a nerve cell, the electrical charge of the signal causes the vesicles of neurotransmitters to fuse with the nerve cell membrane at the very edge of the cell. The neurotransmitters, which now carry the message, are then released from the axon terminal into a fluid-filled space that’s between one nerve cell and the next target cell (another nerve cell, muscle cell or gland).

In this space, called the synaptic junction, the neurotransmitters carry the message across less than 40 nanometers (nm) wide (by comparison, the width of a human hair is about 75,000 nm). Each type of neurotransmitter lands on and binds to a specific receptor on the target cell (like a key that can only fit and work in its partner lock). After binding, the neurotransmitter then triggers a change or action in the target cell, like an electrical signal in another nerve cell, a muscle contraction or the release of hormones from a cell in a gland [3].

There are many different types of neurotransmitters, each with its own unique function and effects on the brain. Some of the most well-known neurotransmitters include dopamine, which is involved in regulating movement, mood, and pleasure; serotonin, which is involved in regulating mood and anxiety; and acetylcholine, which is involved in learning and memory [4].

One of the key roles of neurotransmitters is to regulate communication between neurons. For example, if a person experiences a stressful event, the brain releases a neurotransmitter called norepinephrine. This neurotransmitter excites the neurons and activates the fight or flight response, which prepares the body to respond to the stress. Another important role of neurotransmitters is to regulate brain function. For example, dopamine plays a crucial role in regulating movement and motivation. A lack of dopamine in certain parts of the brain has been linked to Parkinson's disease, a disorder that causes tremors and difficulty with movement. Similarly, low levels of serotonin have been linked to depression, while low levels of acetylcholine have been linked to Alzheimer's disease and other forms of dementia [5].


In conclusion, neurotransmitters play a critical role in regulating brain function and communication. They act as messengers that transmit signals from one neuron to another, allowing the brain to communicate with other parts of the body and regulate different functions, such as movement, mood, and memory. A better understanding of neurotransmitters and their functions can help us develop more effective treatments for brain-related disorders.


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