International Journal of Respiratory Medicine

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Commentary - International Journal of Respiratory Medicine (2023) Volume 8, Issue 2

Pregnancy and Lung Cancer: Balancing Maternal and Foetal Health

Sam Santos*

Department of Gynecology & Obstetrics, University of UZ Leuven Gasthuisberg, Leuven, Belgium

*Corresponding Author:
Sam Santos
Department of Gynecology & Obstetrics
University of UZ Leuven Gasthuisberg
Leuven, Belgium
E-mail: sansam@uzleuven.be

Received: 21-Mar-2023, Manuscript No. AAIJRM-23-95121; Editor assigned: 24-Mar-2023, PreQC No. AAIJRM-23-95121(PQ); Reviewed: 07-Apr-2023, QC No. AAIJRM-23-95121; Revised: 10-Apr-2023, Manuscript No. AAIJRM-23-95121(R); Published: 17-Apr-2023, DOI: 10.35841/aaijrm-8.2.139

Citation: Santos S. Pregnancy and lung cancer: Balancing maternal and foetal health. Int J Respir Med. 2023;8(2):139

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Abstract

Pregnancy is a time when women experience significant changes in their bodies. Unfortunately, this period can also be a challenging time for those diagnosed with lung cancer. Lung cancer is a type of cancer that originates in the lungs and can spread to other parts of the body. It is one of the leading causes of cancer deaths worldwide. In this article, we will discuss the topic of pregnancy and lung cancer, including the challenges that women face when managing both conditions and the potential risks associated with treatment.

Keywords

Pregnancy, Lung Cancer, Chemotherapy, Physiological changes.

Introduction

The diagnosis of lung cancer during pregnancy can be devastating news for women. The treatment of lung cancer usually involves chemotherapy, radiation therapy, and surgery, all of which can harm the developing foetus. Furthermore, pregnant women with lung cancer face unique challenges in managing both conditions. They must balance their own health with the health of their unborn child. Another challenge is the delay in diagnosis due to pregnancy-related symptoms such as shortness of breath and coughing, which are also symptoms of lung cancer. These symptoms may be attributed to the normal physiological changes of pregnancy, making it difficult to diagnose lung cancer early [1].

The treatment options available for pregnant women with lung cancer depend on the stage and type of lung cancer, the gestational age of the foetus, and the overall health of the mother. In some cases, doctors may recommend delaying treatment until after the baby is born. However, this option is not always possible, especially if the cancer is advanced. Chemotherapy is a common treatment for lung cancer, but it can harm the developing foetus. Some chemotherapy drugs can cause birth defects, miscarriage and stillbirth. However, some chemotherapy drugs are safe to use during pregnancy and doctors can adjust the dose and schedule to minimize the risk to the foetus. Radiation therapy is another treatment option, but it is generally avoided during pregnancy because it can harm the developing foetus [2].

Surgery is also a treatment option for lung cancer, but it can be risky during pregnancy. Depending on the stage and location of the cancer, surgery may be delayed until after the baby is born. In some cases, minimally invasive surgery may be an option that minimizes the risk to both the mother and the foetus. The risks associated with treatment for lung cancer during pregnancy depend on the type and stage of cancer, the treatment options, and the gestational age of the foetus. Chemotherapy during the first trimester is associated with a higher risk of birth defects, miscarriage, and stillbirth. However, chemotherapy during the second and third trimesters is less harmful to the foetus [3, 4].

Radiation therapy during pregnancy can harm the developing foetus, especially during the first trimester. However, in some cases, radiation therapy can be used during the second and third trimesters if the benefits to the mother outweigh the risks to the foetus. Surgery during pregnancy is generally avoided during the first trimester because it is associated with a higher risk of miscarriage. However, surgery during the second and third trimesters is generally safe for the mother and the foetus. Overall, the risks associated with treatment for lung cancer during pregnancy must be balanced with the potential benefits. The decision to undergo treatment during pregnancy requires careful consideration and consultation with a multidisciplinary team of healthcare providers, including obstetricians, oncologists, and neonatologists. [5].

Conclusion

Managing lung cancer during pregnancy can be challenging for women, but it is essential to balance maternal health with foetus health. The diagnosis and treatment of lung cancer during pregnancy require a multidisciplinary approach, and the decision to undergo treatment must be made carefully, weighing the risks and benefits for both the mother and the foetus. Early detection of lung cancer in pregnant women is critical to ensure the best possible outcomes for both the mother and the baby.

References

  1. Aloufi D, Baradwan S, AlTurkistany S, et al. Successful pregnancy in a 29-year-old G3P2 shortly after unilateral pneumonectomy and systemic chemotherapy for lung cancer: A case report. Am J Med Case Rep. 2023;24:1
  2. Indexed at, Google Scholar, Cross Ref

  3. He YT, Yang L, Luo WC, et al. Responses to: Pregnancy-associated lung cancer: A clinical and scientific challenge more than treatment dilemma. J ThoraC Dis. 2021;13(10):6102.
  4. Indexed at, Google Scholar, Cross Ref

  5. Ito T, Watanabe N, Watanabe M, et al. Cardiac tamponed during pregnancy due to primary lung cancer: A case report. Obstetric Med. 2022.
  6. Indexed at, Google Scholar, Cross Ref

  7. Montilla F, Le Caer H, Boyer S, et al. Pregnancy and lung cancer: A case report and review of the literature. J Gyn Obst Biol Repr. 2008;37(8):808-10.
  8. Indexed at, Google Scholar, Cross Ref

  9. Scarfone G, Fumagalli M, Imbimbo M, et al. First case report of pregnancy on alectinib in a woman with metastatic ALK-rearranged lung cancer: a case report. J Thorac Oncol. 2021;16(5):873-7.
  10. Indexed at, Google Scholar, Cross Ref

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