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Opinion Article - Journal of Dermatology Research and Skin Care (2023) Volume 7, Issue 1
Nanotechnology's application and potential in aesthetic dermatology.
John Williams*
Department of Dermatology and Venereal Diseases
- *Corresponding Author:
- John Williams
Department of Dermatology and Venereal Diseases
II University of Naples
Naples, Italy
E-mail:W_john@hotmail.com
Received:26-Dec-2022,Manuscript No. AADRSC-23-85089; Editor assigned: 29-Dec-2022, PreQC No. AADRSC-23-85089(PQ); Reviewed:12-Jan-2023, QC No. AADRSC-23-85089; Revised:17-Jan-2023, Manuscript No. AADRSC-23-85089(R); Published:24-Jan-2023, DOI: 10.35841/aadrsc- 7.1.131
Citation: Williams J. Nanotechnology's application and potential in aesthetic dermatology. Dermatol Res Skin Care. 2023; 7(1):131
Abstract
The two most crucial technology of the twenty-first century are biotechnology and nanotechnology, each of which has tremendous room for development and expansion. The creation of Nano scale bimolecular substances and analytical tools for cellular and molecular cell biology research are the academic and industrial goals for these technologies. The field of aesthetic dermatology will have potential to create new biocompatible and biodegradable therapies, delivery systems, and more potent chemicals as a result of advancements in nanotechnology. The basic purpose of cosmetics is to preserve excellent appearance, alter appearance, or eliminate body smells while keeping the skin and its surrounds healthy. Cosmetic dermatology also must stress the parts of cosmetics through understanding the safety and efficacy in promoting good health in light of the changing realities of skin care products. The scientific community may use Nano science to discover more inventive and effective cosmetics. To comprehend how all the parts of the cell cooperate to complete a task, one must have a physical understanding of the cell as a machine.
Keywords
Nanotechnology, Nano biotechnology, Delivery systems, Chitin Nano fibrils, TiO2, ZnO.
Introduction
Ex vivo experiments and cutting-edge laboratory methods must be used to thoroughly investigate the efficacy and safety of novel nanomaterial. Nanostructured TiO2 and ZnO sunscreens, new delivery mechanisms, and natural Nano compounds, including chitin nano-fibrils for healing process, are all being employed successfully in cosmetic dermatology[1].
Significance of nanotechnology and nano-biotechnology
A relatively new field is nanotechnology. Today, nanotechnology is used to produce science-based solutions for novel treatments and cosmetics, improve wellbeing, and address anti-aging issues. It is also crucial for chemical firms with a focus on marketing. The investigation of matter at the atomic or molecular level is known as nanotechnology. Nanotechnology typically deals with structures whose precise dimensions and shape must be determined on a nonmetric scale. A normal atom is around one third of a nanometre, which is one billionth of a metre. A human hair's medial thickness is roughly 10,000 nanometres, but the diameter of an influenza virus is 100 nanometres. The branch of nanotechnology that deals with its biological and biochemical applications or uses is known as Nano biotechnology, which is the interface between nanotechnology and biotechnology[2].
In cosmetic dermatology, nanomaterial
Nanoparticles and nanomaterial have the ability to fundamentally alter how medications and cosmetics work. In particular, nanoparticles are being created to include a variety of skin-beneficial chemicals.
There are two methods used to obtain nanoparticles:
The bottom-up method used to build nanoparticles from the cellular level.
The top-down approach that reduces larger particles by the use of physiochemical methods. In cosmetics the top-down approach is more commonly used to produce different kind of structures. Examples of such structures include nanosomes, autosomes, niosomes, and liposomes.
These labile particles, which range in diameter from 50 to 5000 nm, are utilised to create micro or nano-emulsions that can contain active ingredients while shielding them from oxidation and enhancing their penetration through the epidermal layer[3].
Chitin Nano fibril
A chitin nano-fibril is a nano-crystal of a natural polysaccharide that is isolated from the exoskeleton of crustaceans after the carbonate and protein components have been removed. Chitin nano-fibrils are employed in aesthetic dermatology and bio-textiles because they are quickly digested by the body's endogenous enzymes and have a backbone similar to hyaluronic acid. The crystal is named after a thin needle because of its form and average size of 240 7 5 nm. Furthermore, it is safe to utilise because it occurs naturally and is regarded as a safe raw material. It is biocompatible and eco-friendly because enzymes can break it down quickly. Given that the typical size of the nano-fibril is one-quarter that of a bacterium, 1 g of the product covers 400 m2 of surface area. Many studies have demonstrated that chitin nano-fibrils can stimulate keratinocyte and fibroblast proliferation, controlling not just collagen formation but also cytokine secretion and macrophage activity[4].
Research efforts on cosmetics
Investigate endeavours in restorative dermatology are right now pointed at creating unused naturally neighbourly nano-sized chemicals and unused nano-particulate frameworks for the skin. Subsequently, amid later a long time a few conveyance frameworks have been created for the corrective and dermatological industry, and progressively presented into numerous showcased items. Numerous distinctive dynamic components can be typified in these conveyance frameworks, such as vitamins scents, botanical extricates, and drugs, which have a wide run of corrective or dermatological properties. A few of these conveyance frameworks, such as SLN, are inventive sedate carrier frameworks to begin with outlined for intravenous organization and more as of late examined for perioral and transdermal applications in corrective dermatology. In this way, chemically labile operators ought to be ensured from corruption and the discharge profile balanced. Nano science and Nano engineering seem altogether move forward our understanding of nano-scale forms at the atomic level that happen within the environment. Thus it ought to be conceivable to create unused green innovations that minimize the generation of undesirable by-products discharged into the environment, into squander destinations and streams for case [5].
Conclusion
In any case, to speed up the improvement of both Nano-technology and Nano-biotechnology, multidisciplinary groups of exceedingly prepared individuals with foundations in science, pharmaceutical, connected and computational arithmetic, material science, chemistry, and electrical, chemical and mechanical building will be required. In spite of the current worldwide budgetary emergency, nanotechnology and inventive corrective dermatology, may have the potential to assist reinvigorate a nation’s economy. Be that as it may, separated from making a difference to overcome a few unused challenges in atomic imaging methods, quantitative expository instruments, physical models of the cell as a machine, way better in vivo tests and way better drug/cosmetic conveyance frameworks, nanotechnology might play an critical part within the maintainability of not as it were restorative dermatology but moreover of agribusiness, water sifting, vitality materials, and a clean environment.
References
- Mezzana P.Clinical efficacy of a new chitin nanofibrils-based gel in wound healing. Acta Chir Plast. 2008;50(3):81-4.
- Nasu A, Otsubo Y.Rheology and UV protection properties of suspensions of fine titanium dioxides in a silicone oil.J Colloid Interface Sci. 2006;296(2):558-64.
- Oberdoester G.Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles (vol 113, pg 823, 2005).Environ Health Perspect. 2010;118(9):A380.
- Nohynek GJ, Lademann J, Ribaud C, et al.Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety.Crit Rev Toxicol. 2007;37(3):251-77.
- Gamer A, Leibold E, van Ravenzwaay B.The in vitro absorption of microfine ZnO and TiO2 through porcine skin.Toxicol In Vitro. 2006;20(3):301–307.
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