International Journal of Respiratory Medicine

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Short Communication - International Journal of Respiratory Medicine (2023) Volume 8, Issue 2

Mechanisms of Allergic Rhinitis in Children: Insights into Treatment Strategies

Beibei Bobby*

Department of Otolaryngology Head and Neck Surgery, University of Shijiazhuang, Shijiazhuang, China

*Corresponding Author:
Beibei Bobby
Department of Otolaryngology Head and Neck Surgery
University of Shijiazhuang, Shijiazhuang, China

Received: 28-Mar-2023, Manuscript No. AAIJRM-23-97044; Editor assigned: 31-Mar-2023, PreQC No. AAIJRM-23-97044(PQ); Reviewed: 14-Apr-2023, QC No. AAIJRM-23-97044; Revised: 17-Apr-2023, Manuscript No. AAIJRM-23-97044(R); Published: 24-Apr-2023, DOI: 10.35841/aaijrm-8.2.141

Citation: Bobby B. Mechanisms of allergic rhinitis in children: insights into treatment strategies. Int J Respir Med. 2023;8(2):141

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Respiratory problems in children can range from mild to severe and can be caused by a variety of factors, including infections, allergies, environmental factors and genetic predispositions. Some common respiratory problems in children include. A chronic respiratory disease characterized by inflammation of the airways that causes wheezing, shortness of breath and chest tightness. An infection of the small airways in the lungs, most commonly caused by a virus. It can cause wheezing, coughing and difficulty breathing.


Respiratory problems, Allergies, Environmental factors, Genetic predispositions, Wheezing, Coughing, Breathing.


• Croup: A viral infection that causes inflammation of the larynx, trachea and bronchi, leading to a barking cough, hoarse voice and difficulty breathing.

• Pneumonia: An infection of the lungs that can be caused by bacteria, viruses, or fungi. It can cause cough, fever, chest pain and difficulty breathing.

• Allergic rhinitis: An allergic reaction to airborne particles, such as pollen, dust, or animal dander, that causes nasal congestion, sneezing and runny nose.

• Sleep apnea: A sleep disorder that causes pauses in breathing during sleep, leading to poor sleep quality and daytime sleepiness.

• If your child is experiencing any respiratory problems, it is important to seek medical attention to determine the underlying cause and receive appropriate treatment. There are several types of drugs that are commonly used to treat allergic rhinitis in children. These drugs can be used to alleviate the symptoms of allergic rhinitis, such as sneezing, runny nose and itchy eyes. The following are some of the commonly used allergic rhinitis drugs in children:

• Antihistamines: These drugs block the effects of histamine, which is released by the body in response to an allergen. Antihistamines can relieve symptoms such as itching, sneezing and runny nose. They can be taken orally or used as nasal sprays.

• Intranasal corticosteroids: These are a type of nasal spray that contains corticosteroids, which reduce inflammation in the nasal passages. These drugs are very effective in treating allergic rhinitis symptoms such as nasal congestion, sneezing and runny nose.

• Leukotriene receptor antagonists: These drugs block the effects of leukotriene’s, which are chemicals that cause inflammation in the airways. They can be used in children who have asthma as well as allergic rhinitis.

• Decongestants: These drugs are used to reduce nasal congestion by narrowing the blood vessels in the nasal passages. They are available as nasal sprays or oral tablets, but caution should be used when giving oral decongestants to children as they can cause side effects such as restlessness and irritability.

• Cromolyn sodium: This is a nasal spray that works by preventing the release of histamine and other chemicals that cause inflammation in the nasal passages. It is not as effective as intranasal corticosteroids but can be useful in some children with mild allergic rhinitis. It is important to consult

• A healthcare professional before giving any medication to a child with allergic rhinitis. The appropriate medication and dosage will depend on the child's age, symptoms and medical history.

• Allergic rhinitis, also known as hay fever, is an allergic reaction to allergens such as pollen, dust mites, animal dander, or mould spores. The mechanism of action of allergic rhinitis involves the immune system's response to these allergens.

• When an allergen enters the body, it is recognized as a foreign substance by the immune system, which triggers the release of immunoglobulin E (IgE) antibodies. These antibodies bind to mast cells, which are found in the mucous membranes of the nose, eyes and lungs.

When the allergen comes into contact with the IgE antibodies on the mast cells, it triggers the mast cells to release chemicals such as histamine, leukotriene’s and cytokines. These chemicals cause inflammation of the mucous membranes and increase blood flow to the affected area, leading to the symptoms of allergic rhinitis, such as sneezing, runny nose, itchy eyes and congestion


Over time, repeated exposure to allergens can lead to a chronic inflammatory response, causing long-term damage to the mucous membranes and worsening of symptoms. Treatment for allergic rhinitis typically involves avoiding allergens, using medications to control symptoms and in severe cases, immunotherapy to desensitize the immune system to specific allergens.


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