Journal of Clinical Oncology and Cancer Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (629)348-3199

Opinion Article - Journal of Clinical Oncology and Cancer Research (2022) Volume 5, Issue 3

Design and baseline characteristics of bladder cancer with epidemiology and nutritional determinants

Susanna Wolk*

Department of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden

*Corresponding Author:
Susanna Wolk
Department of Nutritional Epidemiology
The National Institute of Environmental Medicine
Karolinska Institutet, Box 210
SE-171 77 Stockholm, Sweden

Received: 02-Jun-2022, Manuscript No. AACOCR-22-67193; Editor assigned: 03-Jun-2022, PreQC No. AACOCR-22-67193(PQ); Reviewed: 17-Jun-2022, QC No. AACOCR-22-67193; Revised: 20-Jun -2022, Manuscript No. AACOCR-22-67193(R); Published: 27-Jun-2022, DOI:10.35841/aacocr-5.3.113

Citation: Wolk S. Design and baseline characteristics of bladder cancer with epidemiology and nutritional determinants. Allied J Clin Oncol Cancer Res. 2022;5(3):113

Visit for more related articles at Journal of Clinical Oncology and Cancer Research


In 2012, in excess of 400,000 urinary bladder disease cases happened around the world, making it the seventh most normal sort of malignant growth. Albeit numerous past examinations zeroed in on the connection among diet and bladder malignant growth, the proof connected with explicit food things or supplements that could be associated with the advancement of bladder disease stays uncertain. Dietary parts can either be, or alternately be enacted into, expected cancer-causing agents through digestion, or act to forestall cancer-causing agent harm


Osteosarcoma, Bladder cancer, Epidemiology, Diagnosis.


The Bladder disease, Epidemiology and Nutritional Determinants (BLEND) study was set up fully intent on gathering individual patient information from observational examinations on diet and bladder malignant growth. Altogether, information from 11,261 bladder malignant growth cases and 675,532 non-cases from 18 case-control and 6 partner studies from everywhere the world were incorporated with the plan to research the relationship between individual food things, supplements and dietary examples and hazard of creating bladder disease [1].

To blend our information, a typical codebook was made in light of the Eurocode 2 Core characterization form 99/2. The Eurocode 2 Food Coding System was initially evolved to act as a standard instrument for healthful overviews in Europe and to serve the requirement for food consumption examinations inside the European FLAIR Eurofoods-Enfant Project [2]. The Eurocode 2 arrangement System unambiguously characterizes which kinds of food are covered or not inside every food classification with the goal that the potential for misclassification is restricted. The System gives coding to food things devoured everywhere. Coding has been done midway by the analysts of the Blend group [3]. One piece of the group did the coding, while the other piece of the group checked for potential mistakes. Interpretation of the surveys in English was given by the rule specialist to concentrates on in different dialects. Aside from the factors on diet, we gathered non-dietary information, for example, concentrate on plan, age, orientation, ethnic gathering, TNM Classification of Malignant Tumors (TNM), smoking status, smoking recurrence and length, and family ancestry. Every member was relegated an irregular and novel distinguishing proof number. Examinations were limited to grown-ups, for example members more youthful than 18 years were barred. Absolute information have been checked by creating recurrence tables to distinguish erroneous coding while constant information have been actually taken a look at performing clear measurements. Conceivable coding mistakes and missing information inside the gave information of each study were talked about with the essential specialist and refreshed in like manner. Anomalies, characterized as values outside the overall dispersion of the information, were recognized after visual examination of the resultant scatterplots and excluded [4].

A possible justification behind the shortfall of proof between unambiguous food varieties and supplements and the gamble of UBC is that relationship between disease chance and dietary admission are generally feeble and most past examinations might have had lacking example size and in this manner missed satisfactory factual power for definite examinations on individual food things, for subgroup examinations and for food communications. Pooling of individual information of existing epidemiological investigations on diet and UBC could thusly be a powerful method for expanding the on-going information on the impacts of food varieties, supplements and dietary examples on UBC risk. The impact of word related chance and poisons in the water, like arsenic, are not piece of this examination. Word related risk factors were distinguished as chance variables for bladder disease [5].

Be that as it may, as the recurrence of having a high-risk occupation is extremely low (<3%) this couldn't significantly frustrate the outcomes. Thus, the BLEND concentrate as well as most past bladder malignant growth epidemiological examinations have not revised for occupation in their investigations.


Altogether 67 possibly qualified investigations from 156 recovered articles were distinguished. 38 examiners consented to take part and 24 gave information. Purposes behind nonsupport after at first understanding were: no information on diet or the base arrangement of confounders accessible, the responsibility that was at that point too high and the wish to distribute the outcomes on sustenance first prior to partaking in a pooled study. For certain examiners, we lost correspondence after introductory contact. The first datasets and codebooks were gathered in March 2009 while the last dataset was remembered for March 2016. Another two new examinations, one case-control and one accomplice study are accessible for consideration.


  1. Zheng YL, Amr S, Saleh DA, et al. Urinary bladder cancer risk factors in Egypt: a multicenter case–control study. Cancer Epidemiol Biomark Prev: pub Am Assoc Cancer Res, cosponsored Am Soc Prev Oncol. 2012;21(3):537-46.
  2. Indexed at, Google Scholar, Cross Ref

  3. Parkin DM. The global burden of urinary bladder cancer. Scand J Urol Nephrol Suppl. 2008;218:12-20.
  4. Indexed at, Google Scholar, Cross Ref

  5. Riley RD, Lambert PC, Abo-Zaid G. Meta-analysis of individual participant data: rationale, conduct, and reporting. BMJ. 2010;340:c221.
  6. Indexed at, Google Scholar, Cross Ref

  7. Riboli E, Hunt KJ, Slimani N, et al. European prospective investigation into cancer and nutrition (EPIC): study populations and data collection. Public Health Nutr. 2002;5(6B):1113-124.
  8. Indexed at, Google Scholar, Cross Ref

  9. Larsson SC, Andersson SO, Johansson JE, et al. Fruit and vegetable consumption and risk of bladder cancer: a prospective cohort study. Cancer Epidemiol Biomark Prev: pub Am Assoc Cancer Res, cosponsored Am Soc Prev Oncol. 2008;17(9):2519-22.
  10. Indexed at, Google Scholar, Cross Ref

Get the App