Perspective - Archives of General Internal Medicine (2022) Volume 6, Issue 12
Behaviour interactions in endocrinology
Simson Bragg *
Department of Medicine, Northwell Health, United States.
- *Corresponding Author:
- Simson Bragg
Department of Medicine,
Received:30-Nov-2022, Manuscript No. AAAGIM--22-159; Editor assigned: 02-Dec-2022, PreQC No. AAAGIM--22-159 (PQ); Reviewed: 16-Dec-2022, QC No. AAAGIM--22-159; Revised:19-Dec-2022, Manuscript No. AAAGIM--22-159 (R); Published:26-Dec-2022, DOI:10.35841/ aaagim-6.12.159
Citation: : Bragg S. Behaviour interactions in endocrinology. Arch Gen Intern Med. 2022;6(12):159.
Due to the availability of recombinant hormone manufacturing and the development of specialised assays allowing the optimization of dose quantity and treatment schedules, replacement therapy for thyroid, adrenal, and pituitary dysfunction have continued to be improved during the past three decades. The first efficient medical treatment for a particular functional pituitary tumour was made possible by the discovery of the effect of dopamine agonist medication, first bromocriptine, on prolactin hypersecretion. Despite the relatively modest improvement in many patients, the following discovery that bromocriptine has a growth hormone-lowering impact in acromegaly was rightfully considered as a breakthrough.
Recombinant hormone, Pituitary dysfunction, Pituitary tumour.
In a little more than a decade, the widespread use of non-invasive techniques for determining steroid levels in wild primates has changed primate field investigations. Even though interest in the connections between primate hormones and behaviour has a longer history, the majority of the early findings came from studies conducted in captivity where blood or urine samples could be consistently collected from the same subjects over time. Field researchers are now able to examine concerns about hormone-behavior interactions in ways that were previously only conceivable in captive settings because to noninvasive methods for collecting primate endocrinological data . Extending behavioural endocrinological studies to the field has simultaneously allowed researchers to directly compare field and captive results, and it has broadened the research's focus to take into account ecological variables like seasonality, which affects diet and energetics, and reproduction, and may therefore mediate many different types of hormone-behavior interactions that are challenging to detect in captivity. Additionally, field research might shed light on the interactions between social and ecological factors and their impact on hormones [1,2].
Species that exhibit sexual swellings, such as chimpanzees, as well as those whose ovarian condition is more concealed, can both benefit from field endocrinological data because they offer crucial insights into ovarian function and the ways in which social and sexual behaviour patterns change over different phases of female cycles. A special method for assessing developmental processes, such as those of young male and female yellow baboons, is longitudinal monitoring of hormone levels .
Collecting an adequate and appropriate set of hormone samples forbehavioral endocrinological field studies can involve painstaking trade-offsbetween the time, energy, and expense dedicated to the hormonal vs. behavioralcomponents of the work. Some of these trade-offs involve practical decisions, such as whether to stay with a particular subject until he or she defecates and a hormone sample can be collected, or to forfeit the hormone sample to catch up to the rest of the group and resume behavioural sampling on the next focal subject .
Primate behavioural endocrinology field research still mostly focuses on group- or population-specific case studies. Our ability to develop comparative models of monkey behavioural endocrinology is expected to rise as the quantity of studies on relevant topics in other populations and species continues to rise. However, like with other parts of primate field research, certain themes lend themselves more readily to comparison analysis than others because to variations in the time needed to collect the baseline data essential for comparative interpretations .
A wide variety of primate species are now included in behavioural endocrinology field investigations. We foresee the creation of a vibrant new discipline where comparative models of primate behavioural endocrinology give fresh ideas on primates as the scope of these investigations expands.
- Oldfield EH, Doppman JL, Nieman LK, et al.Petrosal sinus sampling with and without corticotrophin-releasing hormone for the differential diagnosis of Cushing's syndrome N Engl J Med. 1991;325:897-905.
- Trainer PJ, Drake WM, Katznelson L, et al.Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med. 2000;342:1171-7.
- Shenker A, Weinstein LS, Moran A, et al. Severe endocrine and non-endocrine manifestations of the McCune-Albright syndrome associated with activating mutations of the stimulatory G protein Gs. J Pediatr. 1993;123:509-518.
- Rosenfeld RG, Rosenbloom AL, Guevara-Aguirre J..Growth hormone insensitivity (GHI) due to primary GH receptor deficiency.Endocr Rev. 1994;15:369-390.
- Freeth JS, Ayling RM, Whatmore AJ, et al. Human skin fibroblasts as a model of growth hormone (GH) action in GH receptor-positive Laron’s syndrome. Endocrinol. 1997;138:55-61.