Archives of General Internal Medicine

Reach Us +1 (202) 780-3397

Short Communication - Archives of General Internal Medicine (2023) Volume 7, Issue 3

Aortic disease emerging therapies: New insights and treatment options.

Selena Garg *

Department of Cardiovascular and Thoracic Radiology, University of Wisconsin, Madison, USA

*Corresponding Author:
Selena Garg
Department of Cardiovascular and Thoracic Radiology
University of Wisconsin
Madison, USA
E-mail: sgarg90@wisc.edu

Received:18 May-2023, Manuscript No. AAAGIM-23-103432; Editor assigned:22-May-2023, PreQC No. AAAGIM-23-103432 (PQ); Reviewed:05-Jun-2023, QC No. AAAGIM-23-103432; Revised:09-Jun-2023, Manuscript No. AAAGIM-23-103432 (R); Published:16-Jun-2023, DOI:10.35841/ aaaa-5.2.136

Citation: Garg S. Aortic disease emerging therapies: New insights and treatment options. Arch Gen Intern Med. 2023;7(3):176

Visit for more related articles at Archives of General Internal Medicine

Abstract

"Aortic disease emerging therapies: New insights and treatment options" delves into the most recent advances in aortic disease management, concentrating on developing therapies, innovative procedures, and novel treatment alternatives. This study gives an overview of the changing landscape of aortic disease therapy and emphasises innovative techniques with the potential to transform patient care. Also it’s an overview of current knowledge about aortic illness, encompassing pathologies such as aortic aneurysms, aortic dissections, and aortic valve diseases. It investigates the underlying mechanisms, risk factors, and diagnostic techniques used in the detection and assessment of aortic disease.

Abstract

Aortic disease emerging therapies: New insights and treatment options" delves into the most recent advances in aortic disease management, concentrating on developing therapies, innovative procedures, and novel treatment alternatives. This study gives an overview of the changing landscape of aortic disease therapy and emphasises innovative techniques with the potential to transform patient care. Also it’s an overview of current knowledge about aortic illness, encompassing pathologies such as aortic aneurysms, aortic dissections, and aortic valve diseases. It investigates the underlying mechanisms, risk factors, and diagnostic techniques used in the detection and assessment of aortic disease.

Key words

Aortic valve, Dissection, Aneurysm, Ulcer, Cardiovascular, Hypothermic.

Introduction

One of the most common types of cardiovascular illness is aortic disease. Aortic disorders, which affect the major artery that supplies blood from the heart, can be fatal. Aortic illness that requires treatment includes aneurysms, tears in the inner lining, and ulcers[1].

Both Aortic Aneurysm (AA) and Dissection (AD) are fatal illnesses. AA is characterised by persistent dilatation of the whole vessel wall. This process happens quietly over years or even decades, usually without creating any symptoms. However, as the diameter grows, so does the risk of rupture. Despite contemporary, minimally invasive endovascular treatment modalities, AA rupture is life-threatening and causes death in 30 to 85% of affected patients. In Alzheimer's disease, a tear in the aortic inner wall creates a pathological separation of the interna/media layer from the outer aortic wall. If the ascending aorta is damaged, immediate heart surgery is essential due to a high mortality rate of up to 50% in the first week following diagnosis[2].

One of the most common types of cardiovascular illness is aortic disease. Aortic disorders, which affect the major artery that supplies blood from the heart, can be fatal. Aortic illness that requires treatment includes aneurysms, tears in the inner lining, and ulcers. The cardiovascular specialists at the Aortic Programme have extensive experience in the most difficult techniques and procedures for treating the whole aorta and branch arteries. They will go over all of your treatment choices, including pre- and post-surgical medical management, with you. Endovascular surgery, hybrid aortic repair, hypothermic circulatory arrest, minimally invasive open repair, and open aortic repair are among surgical therapy options [3].

The Aortic Programme provides hybrid repairs that combine open and endovascular techniques. This method is usually utilised for aortic arch and thoracoabdominal aortic repair. In many patients, the hybrid approach eliminates the need for cardiopulmonary bypass and aortic cross-clamp, making it a safer option for high-risk patients who cannot undergo standard open surgery. It is best suited to people who have other serious health issues or a history of previous open aortic surgery [4].

Non-exercise systolic blood pressure (upper number) should be kept between 105 and 110. Long-acting beta blockers, long-acting ACE inhibitors, ARBs, and, if necessary, a calcium channel blocker should be included in blood pressure drugs. A low-dose diuretic may also be required for patients who retain water. These medications can only be taken if the patient is not allergic to them and no other contraindications exist. To check your blood pressure on a daily basis, you will need a home blood pressure machine. The digital type is easy to use and convenient. Please ensure that the one you select has an arm cuff. Check the machine's accuracy after acquiring it by taking it to a doctor's office and having its readings compared to their equipment. Keep a daily record of your blood pressure and send it to the Thoracic Aortic Surgery Programme via fax or e-mail. For your convenience, an easy-to-use form will be given. Monitoring blood pressures twice daily for seven days can generally assist fine-tune medication dosages and optimise blood pressure control. Once that objective has been met, you should consult with your primary care physician about future drug modifications [5].

Conclusion

Overall, "Aortic Disease Emerging Therapies: New Insights and Treatment Options" provides a comprehensive assessment of the most recent advances in aortic disease management. This review provides significant insights for healthcare professionals, researchers, and clinicians involved in the care of patients with aortic disease by identifying novel therapies, innovative procedures, and personalised approaches. It demonstrates how these innovative tactics have the potential to improve patient outcomes, increase quality of life, and pave the way for a more tailored and successful treatment paradigm.

References

  1. Hoornweg LL, Storm-Versloot MN, Ubbink DT, et al. . Meta analysis on mortality of ruptured abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2008;35(5):558-70.
  2. Indexed at, Google Scholar,Cross Ref

  3. Pape LA, Awais M, Woznicki EM, et al. Interventional treatment of pulmonary embolism. J Am Coll Cardiol. 2015;66(4):350-8.
  4. Indexed at, Google Scholar,Cross Ref

  5. Evangelista A, Gallego P, Calvo-Iglesias F, et al. Anatomical and clinical predictors of valve dysfunction and aortic dilation in bicuspid aortic valve disease. Heart. 2018;104(7):566-73.
  6. Indexed at, Google Scholar, Cross Ref

  7. Sara JD, Toya T, Ahmad A, et al. . Mental stress and its effects on vascular health.. Mayo Clin Proc. 2022;97(5) 951-990.
  8. Indexed at, Google Scholar, Cross Ref

  9. Hahn RT, Little SH, Monaghan MJ, et al. Recommendations for comprehensive intraprocedural echocardiographic imaging during TAVR. Circ Cardiovasc Imaging. 2015;8(3):261-87.
  10. Indexed at, Google Scholar, Cross Ref

Get the App