Microbiology: Current Research

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Short Communication - Microbiology: Current Research (2022) Volume 6, Issue 6

Antivirulence techniques for the natural antibacterial control of foodborne diseases

Abhinav Mishra*

Department of Agricultural Biotechnology, Seoul National University, Seoul, South Korea

Corresponding Author:
Abhinav Mishra
Department of Agricultural Biotechnology
Seoul National University, Seoul, South Korea

Received: 25-Oct-2022, Manuscript No. AAMCR-22-81823; Editor assigned: 27-Oct-2022, Pre QC No. AAMCR-22-81823(PQ); Reviewed: 10-Nov-2022, QC No. AAMCR-22-81823; Revised: 15-Nov-2022, Manuscript No. AAMCR -22-81823(R); Published: 22-Nov-2022, DOI: 10.35841/aamcr-6.6.128

Citation: Mishra A. Antivirulence techniques for the natural antibacterial control of foodborne diseases. J Micro Curr Res. 2022;6(6):128

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Foodborne diseases represent a worldwide health threat other than the incredible monetary misfortunes experienced by the food industry. These hazards require the execution of food safeguarding techniques to control foodborne microbes, the causal specialists of human illnesses. Until now, most control strategies depend on restraining the microbial development or killing the microorganisms by applying deadly medicines. Normal antimicrobials, which repress microbial development, incorporate customary synthetic substances, normally happening antimicrobials or natural conservation (for example valuable microorganisms, bacteriocins, or bacteriophages). Despite the fact that having extraordinary antimicrobial adequacy, challenges because of the variation of foodborne microbes to such control strategies are becoming clear. Such variation empowers the endurance of the microbes in food varieties or food-contact conditions. This basic concern motivates contemporary exploration and food industry area to foster advances which don't target microbial development however incapacitating microbial virulence factors. These advancements referred to as "antivirulence", render the organism non-fit for influencing the infection with exceptionally restricted or no amazing open doors for the pathogenic microorganisms to foster obstruction. For more secure and new like food sources, with no impact on the tangible properties of food sources, a blend of at least two regular antimicrobials or with different stressors, is currently boundless, to save food varieties. This audit presents and basically depicts the conventional versus the arising uses of normal antimicrobials for controlling foodborne pathogens in food varieties.


Food safety, Microbiology, Foodborne pathogens, Food preservation, Antimicrobial technologies, Antivirulence strategy, Natural antimicrobials.


Food is a persevering need, healthfully, for human existence. Be that as it may, unfortunate microorganisms might sully food items, food handling offices or assembling conditions prompting hazard of human diseases. Foodborne microbes are those microorganisms which cause human sicknesses by means of destructiveness apparatus, even in some cases at their low irresistible portion. Control of such microorganisms has advanced through the mankind's set of experiences to take into account augmentation of the food time span of usability, and creation of more secure and nutritious food sources. Microbial control techniques point mostly to repress the development of unwanted microorganisms by means of the utilization of physical or regular antimicrobials-based procedures. In this audit, normal antimicrobials which contain substance and organic based advances will be talked about [1].

Blend of at least two regular antimicrobials or with actual techniques, otherwise called "obstacle approach", acquired the interest of food industry as a result of their negligible effect on the nutritive worth and tangible properties of food sources. Actual techniques for food protection plan to restrain or kill bothersome microorganisms from food varieties or food handling conditions. Research keeps with respect to creating warm handling which is as yet utilized for safeguarding of numerous food varieties until now [2]. While warm handling, in which food sources are warmed up to a specific temperature between 50 to 150 °C, is compelling to kill pathogenic microorganisms, it causes changes in tangible and organoleptic qualities of food sources. Then again, non-warm actual innovations like high tension handling, illumination, and beat electric field have been created, and acquired high shopper acknowledgment since it is less problematic to food quality when contrasted with conventional warm handling. Mix of normal antimicrobials with, especially, non-warm advances will be such a resource in view of the great lethality, they could accomplish, with keeping up with the tangible properties of food sources [3].

In this survey, we mean to basically depict the meaning of normal antimicrobials, and their hidden components, in controlling foodborne microorganisms. Here, normal antimicrobials are classified into those which target; I) Microbial development, and ii) Microbial virulence factors.

Control of microbial growth

The optimal characteristic and extraneous variables fundamental for microbial development in food varieties are designated, so they can't uphold microbial development, or their endurance. Inborn elements are those connected with the actual food, for example pH value, water activity, the nutritional composition, existing antimicrobials or redox potential while extraneous variables incorporate those connected with the climate encompassing the food like capacity temperature, and relative mugginess encompassing the food. Natural antimicrobials control microbial development through disturbance of cell structure and function [4].

Control of microbial virulence

Antivirulence systems have now turned into an arising area of controlling pathogenic microorganisms in food sources. Harmfulness factors are bacterial items by which they stick, colonize, attack, dodge have insusceptible framework or harm the actual host. The creation of destructiveness factors is constrained by different administrative instruments. Of these, majority detecting (QS) is known to direct the creation of a few harmfulness factors when the microbe arrives at high cell thickness, and hence has been an essential objective for hostile to destructiveness specialists. Besides, biofilm shaping capacity is a technique utilized by microorganisms to sidestep the host insusceptible reactions. What's more, appropriate collapsing of destructiveness factors through the bacterial hardware is significant for their organic capabilities. Accordingly, obstruction of destructiveness element's capabilities (for example poison balance) is utilized for antivirulence strategies [5].


  1. Abdelhamid AG, El-Masry SS, El-Dougdoug NK. Probiotic Lactobacillus and Bifidobacterium strains possess safety characteristics, antiviral activities and host adherence factors revealed by genome mining. EPMA J. 2019;10(4):337-50.
  2. Indexed at, Google Scholar, Cross Ref

  3. Singh S, Shalini R. Effect of hurdle technology in food preservation: a review. Crit Rev Food Sci Nutr. 2016;56(4):641-9.
  4. Indexed at, Google Scholar, Cross Ref

  5. Defoirdt T. Quorum-sensing systems as targets for antivirulence therapy. Trends Microbiol. 2018;26(4):313-28.
  6. Indexed at, Google Scholar, Cross Ref

  7. Schütz C, Empting M. Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers. Beilstein J Org Chem. 2018;14(1):2627-45.
  8. Indexed at, Google Scholar, Cross Ref

  9. Watters C, Fleming D, Bishop D, et al. Host responses to biofilm. Prog Mol Biol Transl Sci. 2016;142:193-239.
  10. Indexed at, Google Scholar, Cross Ref

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