Mini Review - Journal of Translational Research (2018) Volume 2, Issue 1
VXc-486 potent drug: A new drug approach in tuberculosis treatment.
Tuberculosis (TB) is a communicable disease sometimes caused by the microorganism mycobacterium tuberculosis (MTB). Anti-tubercular agents inhibit the growth of Mycobacterium tuberculosis. Anti-tubercular agents mainly act by inhibit the growth of bacteria by cell wall synthesis inhibition. VXc-486 is a potent anti-tubercular drug belonging with aminobenzimidazole category. The novel amino-benzimidazole, VXc-486, which targets gyrase B, potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis. VXc-486 is crystalline and flakes in yellow color having solid state. It is crystalline solid at room temperature that show physical characteristic of the drug. VXc-486 is water insoluble potent anti-tubercular drug which is the Amino-benzimidazole family drugAuthor(s): Sharma AK, Sharma V, Rathor R, Khandelwal M, Sharma M