Journal of Pharmaceutical Chemistry & Chemical Science

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article - Journal of Pharmaceutical Chemistry & Chemical Science (2021) Volume 5, Issue 3

Satisfactory access to attain pyrimidoquinoxaline 1,4-dioxide framework of prospective antitumor and antimicrobial activities.

We exploited the utilization of 2-amino-3-cyanoquinoxaline1,4-dioxide 1 to build new series of pyrimidoquinoxaline 1, 4-dioxide derivatives via multicomponent reactions of 1 with DMF-DMA, nbutyl amine, morpholine, Lawesson's reagent, benzoyl chloride. Furthermore, the new synthesized compounds were biologically evaluated for antitumor and antimicrobial activities

Author(s): Wafaa S Hamama*, Sara M Waly, Samy B Said, Hanafi H Zoorob

Abstract Full Text PDF

Get the App