Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1-504-608-2390

- Biomedical Research (2005) Volume 16, Issue 1

Role of ascorbic acid in the prevention of iron-deficiency anaemia in pregnancy

There have been differing reports on the role of dietary ascorbic acid in iron absorption, especially non-heme iron. We measured some haematological and biochemical parameters to establish any correlation between serum ascorbic acid and iron and thus open study line on the need for co-supplementation of the two during antenatal visits to prevent iron-deficiency anaemia in pregnancy. A total of 74 pregnant women aged between 18 and 42 years were recruited for the study. Also 20 age- matched non-pregnant women who were not in their menstrual periods at the time of study were used as control subjects. Blood sample collected from each subject was analyzed for hematological (haemoglobin-Hb, packed cell volume-PCV and mean cell haemoglobin concentration-MCHC) and biochemical (serum iron and ascorbic acid) parameters. Our results showed that 62(83.8%) of the pregnant women were anaemic. The haematological parameters showed no significant differences (p>0.05 for each) between the first trimester and other trimesters. However, they were significantly lower (p<0.05) in the pregnant women of all the trimesters than in the control group. The biochemical parameters showed no significant differences (p>0.05) between the first and second trimesters as well as between each of the two trimesters and the control group but they were significantly lower (p<0.05) in the third trimester than in the first and second trimesters and in the control group. There was no correlation (r=0.03789 for first trimester; r=0.2799 for second trimester and r=0.2568 for con-trol group; p>0.05) between the serum iron and ascorbic acid in the first and second trimesters and the control group. However, there was positive correlation (r=0.6506; p<0.05) between them in the third trimester. We are of the opinion that ascorbic acid plays important role in intestinal absorption of iron, especially in low levels of serum iron.

Author(s): E. N. Shu and S. O. Ogbodo

Abstract Full Text PDF

Get the App