Research Article - Journal of RNA and Genomics (2021) Volume 17, Issue 0

RNA chemistry, non-coding RNAs, siRNAs, miRNAs, transcriptomics, genome editing, genome analysis, functional genomics, epigenomics

Lupeol is a pharmacologically active triterpenoid. It is found in latex of rubber plants and fig trees and also seen in many fruits and vegetables. Lupeol is known as phytosterols. The study is aimed to identify the effect of lupeol on the glucose-6-phosphatase and phosphoenolpyruvate carboxykinase enzyme level in the liver of type-2 diabetic adult male rats. The present study concludes that lupeol regulates glucose-6-phosphatase and phosphoenolpyruvate carboxykinase in high fat diet induced type-2 diabetic male rats. The present study concludes that lupeol regulates glucose-6-phosphatase and phosphoenolpyruvate carboxykinase in high fat diet induced type-2 diabetic male rats. Diabetes is the primary cause of disease such as kidney failure, cardiovascular disease includes stroke and heart attack. They also cause afflictions such as blindness and limb amputation.

Author(s): Sowmya KP, Kavitha S, Selvaraj J, V Vishnupriya, Gayathri R

Abstract PDF