Review Article - Journal of RNA and Genomics (2021) Volume 17, Issue 0

Polychlorinated biphenyls (pcb)-induced changes in the expression of insulin downstream signalling molecules in cardiac tissue of adult male rats.

Persistence and accumulation of numerous toxic substances found in the environment solely resulting from human activity causes abnormality in normal growth and developmental functions of endocrine systems in mammals. Among these xenobiotic endocrine disruptors, PCBs’ (Polychlorinated Biphenyls) effect on living organisms is of great interest. Its immense durable properties are the cause of extensive usage in various industries, which resulted in their wide distribution throughout the ecosystem. Our previous studies have shown that PCB exposure alters glucose homeostasis in skeletal muscle.

Author(s): Saima Hafsah, Kavitha S, V Vishnupriya, J Selvaraj, Gayathri R

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