Journal of Cancer Immunology & Therapy

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Case Report - Journal of Cancer Immunology & Therapy (2019) Volume 2, Issue 1

Nocardiosis in cancer patients

Infections due to Nocardia spp are rare; localized skin forms are often seen among categories with limited exposure, such as agricultural workers. Although uncommon, disseminated infections are severe and life-threatening and affect mainly immunodeficient patients. The most common localization is the lung, but Central Nervous System (CNS), soft tissue, blood, and lymph nodes are also involved in disseminated Nocardiosis. Large series of Nocardiosis are uncommon and often refer to heterogeneous patients with different underlying diseases. Chronic Obstructive Pulmonary Disease (COPD), renal failure, and Diabetes Mellitus (DM) are predisposing factors, as well as immunodeficiency following prolonged steroid therapy, autoimmunity, HIV positivity, cancer, and solid organ or bone marrow transplantation. An unusual case of pulmonary Nocardiosis was diagnosed in a patient of myeloproliferative disease in a young boy of nineteen years. The patient was on treatment on anti-cancer and immunosuppressive drugs since 2018. Rural conditions and environment might have been the source of the Nocardia infection. Timely diagnosis and treatment helped the patient to recover from respiratory infection.

Author(s): Parijat N Goswami, Harsha Panchal, Sonia Parikh, Hitesh Rajpara, Hemang Purohit

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