Mini Review - Addiction & Criminology (2023) Volume 6, Issue 3
Neuroplasticity and drug-seeking behavior: Mechanisms and therapeutic targets.
Drug addiction is a complex and chronic disorder characterized by compulsive drug-seeking
behavior despite adverse consequences. The persistence of drug-seeking behavior is believed to
arise from maladaptive changes in the brain's neural circuitry, particularly in regions involved
in reward, motivation, and decision-making. Neuroplasticity, the brain's ability to reorganize
and modify its structure and function in response to experience, plays a pivotal role in the
development and maintenance of drug addiction. Author(s): Christopher Kalivas*