Commentary - Journal of Gastroenterology and Digestive Diseases (2021) Volume 6, Issue 7

Metagenomic Analysis reveals Patients with COVID-19

COVID-19 remains a significant emerging global ill health, and tiny is understood about the role of oropharynx commensal microbes in infection susceptibility and severity. Here, we present the oropharyngeal microbiota characteristics identified by shotgun meta-genomic sequencing analyses of oropharynx swab specimens from 31 COVID-19 patients, 29 influenza B patients, and 28 healthy controls. Our results revealed a definite oropharyngeal microbiota composition within the COVID-19 patients, characterized by enrichment of opportunistic pathogens like Veillonella and Megasphaera and depletion of Pseudopropionibacterium, Rothia.

Author(s): Jennifer Chennat

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