Mini Review - Biomedical Research (2020) Volume 31, Issue 6
Laboratory diagnosis of SARS COV-2: A mini review.
Real Time Reverse Transcriptase (RT-PCR) has been the gold standard for the diagnosis of COVID 19 infection. However the limitations of the method are false negative results, inability of the method to detect the infection in the early stage, variable results with different samples, variable results when done in different intervals, expensive instrumentation, need for well trained personnel and so on. So, it is the need for the hour to develop a device/method that is sensitive, can detect the cases at the early stage, cost effective, portable so that it will be very useful in resource limited settings. Lab on a chip could be the one such technology.Author(s): Usha Adiga, Varashree BS