Review Article - Journal of Clinical Pathology and Laboratory Medicine (2022) Volume 4, Issue 4
Influence of urinary tract infections in renal sturvite stone.
Struvite stones refers to calculi that form following Urinary Tract Infections (UTIs) caused by urease-producing organisms. Renal struvite stones consist of magnesium ammonium phosphate, carbonate apatite and monoammonium urate. Alkaline urine plays a pivotal role in stone formation. Urinalysis and urine culture are essential for laboratory diagnosis. The relationship between urinary stones and UTIs is well known and shows two different clinical pictures stones that develop following UTIs (infection stones) which play a key role in stone pathogenesis, and stones complicated by UTIs (stones with infection) which are metabolic stones that passively trap bacteria from coexistent UTIs and may consist of calcium or non- calcium. This review article reveals the general characterization of kidney stones, impact of UTIson pathogenesis and Pathophysiology of struvite stone formation and their clinical featuresAuthor(s): Sheena Aliyas1*, Murugan K1, Thanga Mariappan K2