Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-7360-538437

Research Article - Biomedical Research (2017) Volume 28, Issue 7

Efficacy of non-cardioplegic radiofrequency ablation Maze-III procedure (RFA Maze-III) for the treatment of atrial fibrillation (AF) during the valve replacement surgery

Background: The non-cardioplegic surgery has a better myocardial protection compared to cardioplegic surgery. Combination of valve replacement surgery with RFA Maze-III procedure can achieve better clinical efficacy. The goal of this study was to evaluate the efficacy of RAF Maze-III under the noncardioplegic and mild hypothermic Cardiopulmonary Bypass (CPB) condition for the treatment of chronic Atrial Fibrillation (AF) during the valve replacement surgery.

Hypothesis: The non-cardioplegic RFA Maze-III is a safety and efficacy procedure for the treatment of AF during valve replacement surgery.

Methods: From 2007 to 2013, 84 consecutive patients with rheumatic heart disease and chronic AF underwent RFA Maze-III and heart valve replacement surgery in our hospital, 46 of which had noncardioplegic procedure. Continuous electrogram monitoring was performed to observe the cardioelectrical activities of patients during RFA Maze-III and valve replacement surgery. All the patients were follow-up with 24 h Holter and echocardiography in the perioperation and at 12 months after the operation.

Results: Sinus rhythm was recovered and maintained perioperatively in 73.7% (28/38) of cases in the cardioplegic group, which was significantly lower than that (91.3%, 42/46) in the non-cardioplegic group. One year after operation, sinus rhythm was maintained in 78.9% (30/38) of cases with cardioplegic surgery, which was significantly lower than that (89.1%, 41/46), in the group with noncardioplegic surgery.

Conclusion: Mild hypothermic non-cardioplegic surgery is feasible, safe and efficient in the treatment of AF by RFA Maze-III. In addition, non-cardioplegic operation simplifies the surgical procedure and makes the process more clearly.

Author(s): Yang Yan, Lu-Qin Yan, Xiao-Jiang Yu, Wei-Jin Zang

Abstract Full Text PDF

Get the App