Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article - Biomedical Research (2017) Volume 28, Issue 13

Effect of super-early operation on treatment of high-grade ruptured intracranial aneurysm

Objective: To explore the feasibility and clinic value of super-early operation in treatment of high-grade intracranial aneurysm with ruptured hemorrhage.

Methods: From August, 2014 to March, 2016, 46 patients suffering high-grade ruptured intracranial aneurysm were collected. Among them, 23 patients were treated with early operation (operation within 48 or 72 h, group A) while the rest received super-early operation (operation within 24, group B). The differences of effect, post-operation complication, and recovery between groups A and group B were analysed statistically with chi-squire test.

Results: Compare to the 30.43% aneurysms rupture recurrence rate in patients who received early operation (group A), the recurrence rate of aneurysms rupture in patients receiving super-early operation (group B) is lower to 4.35%. Additionally, the post-operation complication rate of group B (8.69%) is significantly lower than that of group A (39.13%). Consistently, 18 out 23 patients in group B recovered very well from the operation, while only 10 out 23 patients in group achieved good recovery.

Conclusion: Super-early operation has certain clinical application value in treatment of high-grade ruptured intracranial aneurysm.

Author(s): Zhenbo Liu, Liguo Qi, Jian Zhu

Abstract Full Text PDF