Research Article - Biomedical Research (2018) Volume 29, Issue 1

Clinical effects assessment of clomiphene on young man hypogonadism patients for adjuvant therapy

It studied the treatment effect of clomiphene using a dosage of 25 mg/time. We recruited 30 young male volunteers of hypogonadism, aged from 22 to 40 y old. By orally once every two days for three months drug intervention, their increased scores of SILOH and IIEF-5 showed that clomiphene could treat they hypogonadism effectively, by increasing expression level of serum total testosterone. This drug could maintain the normal volume of testes, improve sperm motility and increase sperm count, after laboratory testing. So the clomiphene could be recommended to treat young male hypogonadism to improve patients’ symptoms and maintain fertility.

Author(s): Xinshen Zhu, Haipeng Huang, Yuesheng Huang, Denghui Fu

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