Current Pediatric Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +447480022765

Research Article - Current Pediatric Research (2017) Volume 21, Issue 1

Association between low hemoglobin level, vitamin D deficiency and acute lower respiratory tract infections in children aged 6 months to 5 years.

Introduction: Acute lower respiratory infections (ALRIs) contribute to major disease associated mortality and morbidity among children under 5 years. Research suggests that low Hemoglobin (Hb) levels and Vitamin D Deficiency are associated with ALRI. The objective of this study was to know the association of low hemoglobin levels and vitamin D Deficiency with ALRI in children aged 6 months to 5 years. Materials and methods: The present study was a hospital based prospective study conducted over a period of one year, at KIMS Hospital and Research centre, Bengaluru. Children hospitalized for ALRI at KIMS Hospital, Bangalore were included as cases; hospitalized children (6months to 5years) other than respiratory illness were included as controls. Results: Among the cases, Vitamin D Deficiency, Vitamin D Insufficiency and Normal Vitamin D levels were seen in 70% (n=35), 28% (n=14), 2% (n=1) children respectively with Mean ± SD Vitamin D levels of 17.66 ± 5.53 ng/ml while controls had 16% (n=8), 24% (n=12), 60% (n=30) children respectively with a Mean ± SD Vitamin D level of 34.38 ± 13.87 ng/ml with p value <0.001. Among cases 48% (n=24) and 52% (n=26) children had Hb levels below 11g/dl and Hb above 11 g/dl respectively. While among controls 28% (n=14) and 72% (n=36) children had Hb below 11g/dl, and Hb above 11 g/dl, respectively. We found a significant correlation between Vitamin D levels and severity of ALRI with a p value of 0.03, a significant correlation between severity of ALRI and Hb levels with a p value of <0.01 and a significant correlation between Severe ALRI and combined low Hb and Vitamin D deficiency with p<0.0007. Conclusion: The study shows a significant correlation between low Hb levels and Vitamin D deficiency with increased susceptibility to ALRI. Severity of ALRI is inversely related to Vitamin D levels and Hemoglobin levels and more severe with combined deficiency.

Author(s): Madhu GN, Siva Saranappa SB, Manasa G

Abstract Full Text PDF