Research Article - Allied Journal of Clinical Pathology Research (2017) Volume 1, Issue 1
Relationship between Finnish diabetes risk score and metabolic syndrome, vitamin d and insulin resistance in women.
Objective: The Finnish Diabetes Risk Score (FINDRISC) is thought to be associated with cardiovascular risk factors separately from type 2 diabetes. We aimed to evaluate the relationship between FINDRISC and metabolic syndrome, vitamin D and insulin resistance in this study. Methods: 115 women were recruited to study. Patients were divided into 5 groups according to FINDRISC score. Metabolic syndrome was assessed in patients with FINDRISC scores, body mass index (BMI), fasting blood glucose (FBG), HbA1c, insulin resistance index (HOMA-IR), high density lipoprotein cholesterol (HDL), triglyceride (TG), systolic and diastolic hypertension. Results: The mean age of the patients was 30.5 ± 9 years, BMI was 32.4 ± 6.2 kg/m2, waist circumference was 98 ± 13 cm. HDL: 46.6 ± 9, HOMA-IR: 3.6 ± 2. There were (n=34) patients with metabolic syndrome and (n=81) patients without metabolic Syndrome. Patients were divided into 5 groups according to FINDRISC score. There was a significant positive correlation between metabolic syndrome and FINDISC score (Pearson Chi-square r=0.350, P=0.001). There was a significant difference between FINDRISC score and age, waist circumference, BMI, HbA1c, HOMA-IR, HDL, systolic and diastolic tension (P<0.05). There was no significant difference between FINDRISC Score vitamin D and TG. There was a positive correlation between FINDRISC score and FBG, HbA1c, HOMA-IR, triglyceride, systolic and diastolic blood pressure (P<0.05).There was a negative correlation between FINDRISC score and HDL (Person correlation r=-0.257, P=0.008). Conclusions: Metabolic syndrome in women is associated with increased FINDRISC score. No correlation was found between vitamin D levels and FINDRISC. FINDRISC is not only related with Type 2 DM also associated with cardiovascular risk factors, Systolic-diastolic tension, HDL-C and TG disorder.Author(s): Ahmet Nalbant