Research Article - Gynecology and Reproductive Endocrinology (2017) Volume 1, Issue 1
Maternal morbidity with early onset hypertensive disorders during pregnancy
Background: Hypertensive disorders of pregnancy (HDsP) are being divided into early onset
(EO), late onset (LO) disorders, depending upon gestation at diagnosis, because of differences in
causes, pathology, outcome and sequale. It seems EO HDsP cause much more morbidity in the
Objective: To know differences in maternal morbidity EO HDsP compared to late onset
Material Method: Study was done to know complications in cases of 1046 cases of EO LO HDsP,
managed over 2 years, 11.73% of 8920 births during the study period. EO cases were (Category
A)-20 to <28 weeks, (B) ? 28-<34 weeks and LO, (C) ? 34-<37 weeks, (D) ? 37 weeks.
Results: Significantly more women with EO HDsP were primigravida of younger age.
Significantly more women with very EO HDsP (Category A) had liver dysfunction compared to
Category B, C, D, 85% had mild preeclampsia, 60% severe in A, 32% mild PE 27% severe PE, in
LO cases, 9.58% mild PE, 50% severe PE in C, 19.56% mild PE in D, 44.11% severe PE. HELLP
(Hemolysis, Elevated Liver enzymes and Low Platelet count) as well as renal failure were also
more often diagnosed in EO cases. In LO no patient had grade III hypertensive retinopathy.
Placental abruption occurred in 25% A, 14.66% B, 3.79% C, 2.67% D. There was no maternal
death with individualized management.
Conclusion: Younger women had EO disorders which were more often severe. There were more
chances of multiorgan disorders in women with EO disorders compared to LO. Author(s): Chhabra S and Singh A
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