Research Paper - Archives of General Internal Medicine (2018) Volume 2, Issue 3
Iron Deficiency Anemia in Children with Congenital Heart Disease and the Usefulness of Erythrocyte Indexes as a Screening Tool.
Introduction: The iron deficiency anemia (IDA) is the most common micronutrient malnutrition
in the world. This condition has been shown to increase morbidity in adults and to exert negative
impact on the psycho-motor development in children. The IDA in children with congenital heart
disease (CHD) with its negative consequence has been recognized for a long time but in clinical
practice the issue does not gain sufficient attention in developing countries.
Objectives: We conducted this study to investigate the prevalence of IDA in children with CHD
and to assess the diagnostic values of hemogram, especially the erythrocyte indexes as a simple
tool for early recognition of IDA.
Materials and methods: Children under 15 years old with confirmed CHD admitted to the Unit
of Pediatric Cardiology, Cardiovascular Center, University Medical Center, Ho Chi Minh City
from August 2016 to March 2017 were recr uited. The total blood cell count, serum iron, ferritin
and transferrin were measured preoperatively.
Results: There were 69 pediatric patients were recruited in which 36 children with cyanotic
CHD and 33 children with acyanotic CHD. There were 11.1% of children with cyanotic CHD
and 3% of children with acyanotic CHD who showed true IDA. The prevalence of depletion or
reduction of body iron store was very high. Up to 77.8% of children with cyanotic CHD and
87.2% children with acyanotic CHD were at risk of iron deficiency. The erythrocyte indexes
proved to be useful as simple tool for detecting IDA in children with cyanotic CHD.
Conclusion: IN the present investigation, the prevalence of IDA was found high in the children
with CHD. The total blood cell count and erythrocyte indexes were of suggestive value for
diagnosis of IDA. Iron supplement treatment should be recommended in this group of patients. Author(s): Truong Quang Binh, Nguyen Thi Bang Suong, Nguyen Hoang Dinh, Vo Tuan Anh, Vu Tri Thanh, Le Minh Khoi
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