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Histomorphological spectrum of meningioma with variants and grading

Introduction: Meningiomas are a histologically diverse group of tumors derived from meningothelial cells. In this present study the clinical features, anatomical location, and histopathological spectrum of Meningioma were studied. Materials and Methods: The study included 103 CNS tumors operated during a one year period in various hospitals and clinics of dhaka, Bangladesh. All the cases of meningioma were studied by histopathological examination using H&E staining. Results: In this study, the most common age group was 40-49 years (35%). Female predominance (73.8%) was noted. Intracranial meningiomas (90.90%) were common than spinal meningiomas. The most common histopathological type was meningotheliomatous meningioma (50%). 94.3% of the meningioma was WHO grade I tumor. Conclusion: Meningiomas display a wide diversity of histopathological appearances. The majority are benign and hence curable by surgical resection. A few histological features and variants are associated with aggressive behavior and high risk of recurrence. Thus accurate histopathological diagnosis and grading of these tumors are essential.

Author(s): Abu Khalid Muhammad Maruf Raza ,Ferdous Ahmed, Tajrin Akter Munni,Zabed Ahmed Mitu,Shahriar Masood