Biomedical Research

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Effectiveness and safety of ancillary device for endoscopic submucosal dissection

Objective: Endoscopic Submucosal Dissection (ESD) can be used to resect gastrointestinal diseases, but ESD costs long procedure time. It was reported that the rulers can serve as an ancillary device for shortening the procedure time. Thus, we aimed to identify a ruler assisted method performed by endoscopic nurses to shorten ESD procedure time and improve safety.

Methods: A total of 30 patients indicated for ESD in our hospital from January 2016 to May 2016 were prospectively enrolled and randomly divided into control and experimental group, which received routine and ruler assisted intervention, respectively. We compared the demographic and clinical characteristics, procedure time and perioperative complications between two groups, analyzed the application of ancillary device assisted ESD.

Results: There were 12 male and 3 female patients in control group. The diameter of the resected lesions was over 2.5 cm, and the maximal circumference was 9 cm. In experimental group, there were 6 male and 9 female patients. The diameter of the resected lesions was also over 2.5 cm, and the maximal circumference was 11 cm. The procedure time ranged from 45 to 90 min in control group, which ranged from 30 to 80 min in experimental group. There were no significantly statistical differences on the size of the resected specimen between the two groups. No obvious bleeding and perforation were observed.

Conclusions: Our prospective data proved that the ruler assisted endoscopic device for ESD is safe and effective in shortening procedure time and avoiding mucosal injuries and complications.

Author(s): Yang Xu, Weiqing Shi, Xueting Zhang, Hanqin Zhang, Teng Yang, Aitong Li, Ranyun Zhou