Moyamoya disease is a rare cerebrovascular syndrome characterized by progressive stenosis and occlusion of the internal carotid arteries and other circle of Willis blood vessels. There is a growing body of research on Moyamoya, but very little describing clinical and functional outcome post rehabilitation treatment. This case series describes two individuals with Moyamoya who were in their 30’s, college education, high functioning, and healthy and without any neurological history until they suffered acute intraventricular hemorrhages in physical and cognitive impairments. Both individuals showed impairments in short-term memory and higher level attention including alternating attention. Both received transdisciplinary treatment for 3 to 4 months, showed cognitive and physical recovery, and were able to return to successfully their careers. Based on these cases it appears reasonable to assume that despite the anomalous blood vessel development, some individual with this disorder may have very good stroke recoveries, though it may need follow up due to possible risk of needing a surgical intervention.