Biomedical Research

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Biofabrication of Zinc oxide nanoparticles and their in-vitro cytotoxicity towards gastric cancer (MGC803) cell

This present report describes the green approach for the preparation of zinc oxide nanoparticles (ZnO NPs) using Murraya keenigii leaf extract by an eco-friendly approach. The produced ZnO NPs were characterized by using techniques such as X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR), Ultra Violet-Visible (UV-Vis), Energy Dispersive Spectroscopy (EDS) and Transmission Electron Microscopy (TEM). TEM and Dynamic Light Scattering (DLS) results have confirmed the formation of spherical ZnO NPs with average size of 20 nm. Further, the cytotoxicity results of the synthesized ZnO NPs showed their excellent biocompatibility towards gastric cancer (MGC803) cell lines, extending their scope of applications in biomedicine.

Author(s): Chongyao Bi, Jianwei Li, Lijun Peng, Jianmin Zhang