Journal of Physical Therapy and Sports Medicine

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Journal of Physical Therapy and Sports Medicine 44 7897 074717

Thrombocytes-12

Thrombocytes are also called as blood platelets whose purpose is the clotting of blood. These are the non-nucleus constructions attained from the megakaryocytes of the bone marrow, and then enter into blood movement. The core purpose of thrombocytes is stopping bleeding. Thrombocytes (platelets) play an important role in haemostasis, by plugging and repairing damaged blood vessels, thus preventing blood loss. They also participate in a cascade of events that leads to blood clotting by triggering the release of a series of coagulation factors. In the first step, platelets are activated by several materials, including collagen from injured skin, as well as ADP (adenosine diphosphate) and thromboxane A2, secreted by activated platelets. Activation causes platelets to become adhesive, which facilitates their attachment to damaged tissues and to each other to form clumps. The penultimate step in coagulation is the formation of fibrin from fibrinogen. Fibrin filaments enmesh platelets and red and white blood cells to form a plug, which contracts to form a clot. \Since this is a multi-step procedure, discrete in vitro tests are frequently approved out for inhibition of platelet combination by collagen, ADP, arachidonic acid, or other substrates.

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