Asian Journal of Biomedical and Pharmaceutical Sciences

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The green synthesis and antibacterial efficacy of CuO and ZnO nanoparticles against Gram-positive and Gram-negative bacteria

Joint Event on World Summit on Healthcare & Hospital Management & International Conference & Exhibition onBiologics and Biosimilars
March 26-27, 2018 | Orlando, USA

Mohammad F

Aligarh Muslim University, India

Posters & Accepted Abstracts : Asian J Biomed Pharmaceut Sci


Infectious diseases possess a big challenge for the scientists worldwide. Antibiotics were once a boon for mankind to combat the infectious diseases. However, the emergence of antibiotic resistance among superbugs is matter of great concern throughout the world. Recent advances in the field of nanotechnology particularly synthesis of metal nanoparticles of specific size and shape are suggestive of bright future of these materials. Nano-sized particles of the metal oxides viz. CuO and ZnO were successfully synthesized using aqueous and alcoholic extracts of Swertia chirayita as a reductant and stabilizer. The as-prepared nanoparticles were further characterized by using Fourier transform infrared spectroscopy, X-ray diffraction, UVvisible spectroscopy, high-resolution transmission electron microscopy, scanning electron microscopy and energy-dispersive X-ray spectroscopy. These nanoparticles were evaluated for their antibacterial efficacy against Gram-positive (Staphylococcus aureus) as well as Gram-negative (Escherichia coli and Salmonella enterica) bacterial strains. Among the two metal oxides, CuO nanoparticles showed better antibacterial efficacy as compared to ZnO nanoparticles against both the Gram-positive and Gramnegative bacterial strains. e:


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