3'-Poly(A) tail enhances siRNA activity against exogenous reporter genes in MCF-7 cells
Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Haidian District, Beijing 100850, China
Biography:
Beifen Shen, male, Han nationality, was born in 1943. His ancestral home is Kunshan, Jiangsu Province and graduated from the Biological Department of Fudan University. His research interests include basic RNA studies (RNAi mechanisms, structure and function of HIV-1 RNA) and applied research (RNAi-based gene therapy for HIV-AIDS, novel gene expression switches and live-attenuated vaccine designs).
Subjects of specialization: siRNA, poly(A) tail, non-specific, enhanced gene silencing, Argonaute