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Journal of Timely Topics in Clinical Immunology | Volume 2

July 26-28, 2018 | Moscow, Russia

Immunology

Annual Congress on

High CD8 cell percentage and HCV control in HIV-1 controllers and HTLV-2 coinfected patients

Alejandro Vallejo

Ramón y Cajal University Hospital, Spain

atural control of HIV-1 infection occurs in less than

1% of patients, maintaining very low plasma HIV-

1 RNA loads or even below the limit of detection, and

usually with no clinical signs of disease progression

for many years without any antiretroviral treatment.

HTLV-2/HIV-1 co-infection is found with relatively high

frequency among injection drug users in North America and

Western Europe. These patients have been reported to have

lower levels of plasma HIV-1 RNA loads before antiretroviral

treatment, and slower decrease of CD4 T cell counts. These

two groups of patients show an immune capacity that

enables a certain control of viral infections, dramatic control

of HIV-1 replication in the case of controllers. The aim of this

study was to compare viral and immunologic parameters

between HIV-1 controllers (N=75), HTLV-2/HIV-1 chronic

progressors (N=57), and HIV-1 chronic progressors (N=182).

Speaker Biography

Alejandro Vallejo is a biologist and completed his PhD at Complutense University,

Madrid, Spain. One of his fields of research is the study of immune parameters of HTLV

infections among HIV-1 infected patients. He moved to the Laboratory of Molecular

Virology, CBER, Food and Drug Administration, Bethesda, MD, USA, as a Post-Doctoral

Fellow (1995-2000) and developed several works on molecular epidemiology of HTLV

and HIV, and viral tropism. Then he joined the Immunovirology Laboratory at the Virgen

del Rocío University Hospital, Seville, Spain, as an independent researcher (2000-2008).

He focused his research on immune recovery of HIV-1-infected patients. Then he

moved to Ramon y Cajal University Hospital in Madrid to follow his research on HIV-1

immunopathology and continuing the research on HTLV-1/2 infections (2008) running

the Laboratory of Molecular Virology within the Infectious Diseases Department.