Journal of Parasitic Diseases: Diagnosis and Therapy

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Short Communication - Journal of Parasitic Diseases: Diagnosis and Therapy (2023) Volume 8, Issue 1

The role of bacterial biofilm in antibiotic resistance and food contamination.

Arturo Anne*

Department of Medicine, and Department of Microbiology, Albert Einstein College of Medicine, Bronx, New York

*Corresponding Author:
Mbamalu ON
Department of Medicine and Department of Microbiology
Albert Einstein College of Medicine, Bronx, New York

Received: 09-Jan-2023, Manuscript No. AAPDDT-23-87430; Editor assigned: 10-Jan 2023, PreQC No. AAPDDT-23-87430(PQ); Reviewed: 20-Jan-2023, QC No. AAPDDT-23-87430; Revised: 22-Jan-2023, Manuscript No. AAPDDT-23-87430(R); Published: 28-Jan-2023, DOI: 10.35841/2591-7846-8.1.134

Citation: Anne A. The role of bacterial biofilm in antibiotic resistance and food contamination. J Parasit Dis Diagn Ther 2023;8(1):134


Biofilm is an important hassle within the clinical area seeing that it's far shaped on clinical implants inside human tissue and worried in a large number of great continual infections. Food and meals processing surface grow to be a super surroundings for biofilm formation in which there are sufficient nutrients for microbial increase and attachment. Therefore, biofilm formation on these surfaces, in particular on meals processing floor becomes an assignment in meals protection and human health. Microorganisms within a biofilm are encased inside a matrix of extracellular polymeric materials which can act as a barrier and recalcitrant for distinctive hostile conditions such as sanitizers, antibiotics, and different hygienic conditions.


Microorganisms, Antibiotics, Sanitizers, Infections.


Food infection may also arise during any step inside the farmto- fork continuum from environmental, animal, or human sources and motive foodborne sickness and intoxication. Biofilm formation with the aid of foodborne pathogens is an inevitable occasion and turns into a supply of meals infection. Bacterial biofilm formation is considered to be an emergent and prevailing microbial lifestyle in herbal and manmade environments and happens on all surface sorts. Biofilm is one of the greatest and maximum successful existence bureaucracies on Earth. In nature, microorganisms normally exist within the shelter of extraordinarily hydrated biofilms which creates a conducive environment for cells to stick collectively and onto all kinds of surfaces [1].

Because microorganisms within this community produce a cement-like matrix that can act as a “biological superglue”, to fix or entice onto distinct biotic or abiotic surfaces. For instance, biofilm infections on implants or indwelling devices are tough to get rid of due to their plenty better safety towards macrophages and antibiotics, main to intense scientific complications frequently with lethal final results. Generally, they persist and exist in food processing environments in which they turn out to be a source of move-contamination and foodborne diseases. The different vital difficulty with biofilm formation is their antibiotic resistance which makes medicinal drug tough, and they use extraordinary physical, physiological, and gene-associated elements to develop their resistance mechanisms [2].

Biofilm formation is typically regarded as a cooperative corporation, wherein lines and species paintings together for a commonplace goal. For this cooperative pastime, there must be a cell-to-cellular communique. This mobile-to-cell conversation mechanism in the microbial community is referred to as quorum sensing wherein microorganisms use signalling which includes acyl-homoserine lactone in Gram-poor microorganisms, the auto inducing peptide in Gram-high-quality microorganisms, and the autoinducer-2 in both Gram-negative and -tremendous bacteria for a specific reason [3].

Quorum sensing gadget is a mechanism via which microorganisms alter the gene expression profile in line with the scale of the microbial populace, causing the formation of various sorts of biofilm. As a well-known quorum sensing is a manner via which microorganism produce and stumble on signal molecules and thereby coordinate their conduct in a mobile-density-structured way. Biofilm production can be influenced by a variety of things along with surface conditions, chemical and physical increase factors, cellular structures, and every other demanding situation [4].

The interaction between those and different elements determines its fate. As structural and physiological change takes location after cells were connected to conditioned surfaces. Structural polymeric materials produced are appearing as a barrier and prevent the entrance of antibiotics and sanitizer retailers [5].


Food contamination has been attributed to biofilms which are microbial communities dwelling together that can be attached to biotic and abiotic surfaces. Once they connected irreversibly on these surfaces, they expand mature systems that act as a barrier towards sanitizer and different marketers. Consequently, they will be a source of post contamination on later degrees and proof against harsh environmental situations such as sanitizer. The surface wherein foods can be processed must be wiped clean and disinfected regularly using appropriate and powerful sanitizers which could disrupt microbial cells and their attachment on food surfaces and environments. The nature of the floor wherein foods can be processed is likewise paramount for biofilm formation. Therefore, it's far higher to design suitable materials the usage of technology in an effort to reduce microbial attachment and conducive for cleansing. In addition to applying sanitizers and different marketers, it is better additionally to apprehend their genes which might be concerned in encoding microbial cellular surfaces which might be essential for attachment.


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