Research and Reports in Pulmonology

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-1518-081136

Perspective - Research and Reports in Pulmonology (2023) Volume 4, Issue 3

The link between allergies and asthma: Exploring the connection.

Ken Suzukawa*

Clinical Research Center, National Hospital Organization Tokyo National Hospital, Takeoka, Kiyose-City, Tokyo, Japan

*Corresponding Author:
Ken Suzukawa
Clinical Research Center
National Hospital Organization Tokyo National Hospital
Takeoka, Kiyose-City, Tokyo, Japan

Received: 30-May-2023, Manuscript No. AARRP-23-103847; Editor assigned: 01-June-2023, PreQC No. AARRP-23-103847 (PQ); Reviewed: 15-June-2023, QC No. AARRP-23-103847; Revised: 20-June-2023, Manuscript No. AARRP-23-103847 (R); Published: 27-June-2023, DOI: 10.35841/aarrp-4.3.149

Citation: Suzukawa K. The link between allergies and asthma: Exploring the connection. Res Rep Pulmonol. 2023;4(3):149

Visit for more related articles at Research and Reports in Pulmonology


Allergies and asthma are chronic respiratory conditions that often coexist. Many individuals who suffer from allergies find themselves also battling asthma symptoms. This article aims to explore the intricate link between allergies and asthma, shedding light on the underlying mechanisms, common triggers, and treatment approaches. Understanding this connection is crucial for effective management and improving the quality of life for those affected by these conditions. Allergies are hypersensitive reactions of the immune system to substances known as allergens. Common allergens include pollen, dust mites, pet dander, mold spores, and certain foods. When an allergic individual comes into contact with an allergen, the immune system mounts an exaggerated response, leading to the release of various chemicals, such as histamine, which causes typical allergy symptoms like sneezing, itching, and watery eyes [1].

Asthma, on the other hand, is a chronic inflammatory disease of the airways characterized by recurrent episodes of coughing, wheezing, shortness of breath, and chest tightness. Inflammation and increased sensitivity of the airways make them highly responsive to triggers, leading to narrowing of the air passages and difficulty in breathing. Both allergies and asthma share a common underlying pathophysiology involving an immune system overreaction and inflammation. In allergic reactions, exposure to an allergen triggers the release of immunoglobulin E (IgE) antibodies, which bind to mast cells and basophils. Upon subsequent exposure to the same allergen, these cells release inflammatory mediators, including histamine, leukotrienes, and cytokines, causing allergic symptoms [2].

In asthma, the immune response to allergens or other triggers leads to the release of similar inflammatory mediators, resulting in airway inflammation. This inflammation causes the airway muscles to contract and the airway lining to become swollen and produce excess mucus, leading to the characteristic symptoms of asthma. Allergens play a significant role in triggering both allergies and asthma. Pollen, dust mites, pet dander, mold spores, and certain foods are common allergens that can induce allergic reactions in sensitive individuals. In some cases, exposure to these allergens can also trigger or worsen asthma symptoms, leading to a condition known as allergic asthma [3].

Individuals with allergic asthma experience asthma symptoms when exposed to specific allergens. The immune response triggered by these allergens contributes to the underlying inflammation of the airways, exacerbating asthma symptoms. Managing allergic triggers is crucial for effectively managing asthma in individuals with allergic asthma. Allergies can significantly impact the severity of asthma symptoms. When individuals with asthma are exposed to allergens to which they are allergic, it can worsen their asthma symptoms and increase the frequency and intensity of asthma attacks. Allergens can act as triggers, leading to airway inflammation and making the airways more sensitive and reactive [4].

Furthermore, the presence of allergies in individuals with asthma can make asthma more difficult to control, requiring more aggressive treatment approaches. Addressing and managing allergies is essential in these cases to improve asthma control and reduce the frequency and severity of asthma attacks. To effectively manage allergies and asthma, an integrated approach is necessary. This approach involves identifying and avoiding allergens whenever possible, using preventive measures such as air purifiers and allergen-proof bedding, and adopting appropriate medical interventions [5].


The link between allergies and asthma is multifaceted, with shared underlying mechanisms and common triggers. Understanding and managing allergies is crucial for effective asthma management. By identifying and avoiding allergens, adopting preventive strategies, and seeking appropriate medical interventions, individuals can effectively manage both allergies and asthma, improving their quality of life.


  1. Murdoch JR, Lloyd CM. Chronic inflammation and asthma. Fundam  Mol Mech  Mutagen. 2010;690(1-2):24-39.
  2. Indexed at, Google Scholar, Cross Ref

  3. Calixto MC, Lintomen L, Schenka A, et al. Obesity enhances eosinophilic inflammation in a murine model of allergic asthma. Br J Pharmacol. 2010;159(3):617-25.
  4. Indexed at, Google Scholar, Cross Ref

  5. Perkins TN, Oczypok EA, Dutz RE, et al. The receptor for advanced glycation end products is a critical mediator of type 2 cytokine signaling in the lungs. J Allergy Clin Immunol. 2019;144(3):796-808.
  6. Indexed at, Google Scholar, Cross Ref

  7. Kinsky OR, Hargraves TL, Anumol T, et al. Metformin scavenges methylglyoxal to form a novel imidazolinone metabolite in humans. Chem Res Toxicol. 2016;29(2):227-34.
  8. Indexed at, Google Scholar, Cross Ref

  9. Koulis C, Watson AM, Gray SP, et al. Linking RAGE and Nox in diabetic micro-and macrovascular complications. Diabetes Metab. 2015;41(4):272-81.
  10. Indexed at, Google Scholar, Cross Ref

Get the App