Mini Review - Journal of Plant Biotechnology and Microbiology (2023) Volume 6, Issue 1
The Impact of Antibiotic Resistance on Microbial PathogenesisSheung Hou*
Division of Genetics and Plant Breeding, Lingnan University, Lingnan, Tuen Mun, Hong Kong
- *Corresponding Author:
- Sheung Hou
Division of Genetics and Plant Breeding
Lingnan University, Lingnan
Tuen Mun, Hong Kong
Received: 30-Jan-2023, Manuscript No. AAPBM-23- 88997; Editor assigned: 31-Jan-2023, PreQC No.AAPBM-23- 88997(PQ); Reviewed: 15-Feb-2023, QC No.AAPBM-23-88997; Revised: 18-Feb-2023, Manuscript No. AAPBM-23- 88997(R); Published: 28-Feb-2023, DOI: 10.35841/aapbm-6.1.135
Citation: Hou S. The impact of antibiotic resistance on microbial pathogenesis. J Plant Bio Technol. 2023;6(1):135
Antibiotic resistance is a growing public health concern that has serious implications for the management of infectious diseases. The overuse and misuse of antibiotics has led to the evolution of antibiotic-resistant strains of bacteria, making it increasingly difficult to treat infections effectively. This phenomenon has profound consequences for the treatment of bacterial infections and the management of microbial pathogenesis. Antibiotic resistance occurs when bacteria evolve to survive exposure to antibiotics that were previously effective in killing them. This can happen through a variety of mechanisms, such as the acquisition of resistance genes through horizontal gene transfer, changes in the target site for the antibiotic, or the production of enzymes that break down the antibiotic. As a result, antibiotics that were once effective at killing bacteria now become ineffective, leading to the emergence of antibiotic-resistant strains .
Anti-toxins principally follow up on bacterial development by taking out microorganisms or keeping them from recreating and spreading. In any case, since they do as such at various rates, the excess microscopic organisms might transform on the off chance that the portion is deficient and oppose anti-microbial treatment through regular determination. Antimicrobial obstruction (AMR) is presently a serious danger to human wellbeing since antimicrobial medications are turning out to be dynamically less successful, and there are as of now scarcely any new classes of anti-toxins in the drug chain. The latest new class of anti-infection agents was found in 1987; from that point forward, just five new classes of anti-microbials have been effectively acquainted with the market. Besides, not a single one of them target Gram-negative microscopic organisms, which cause probably the most lethal and challenging to-treat diseases in clinic settings. The survey investigates why and how antimicrobial obstruction is turning out to be a particularly difficult issue. The creators stress the significance of leading precise examinations and appraisals of the effect of antimicrobial opposition on death, length of emergency clinic stay, and medical care expenses to lay out compelling observation frameworks .
The impact of antibiotic resistance on microbial pathogenesis is significant. The increasing prevalence of antibiotic-resistant strains of bacteria makes it more difficult to treat infections, and increases the risk of morbidity and mortality. In some cases, it can lead to the development of life-threatening infections that are difficult or impossible to treat, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). The emergence of antibiotic-resistant strains also has a significant impact on public health. It increases the cost of healthcare, as more expensive and toxic antibiotics are required to treat infections, and prolongs hospital stays, leading to higher costs for patients and the healthcare system. In addition, the spread of antibiotic-resistant strains can result in the emergence of new, more virulent infections that are difficult to control and prevent .
The development of antibiotic resistance also has serious implications for the future of medicine. Antibiotics are essential for many medical procedures, such as surgery and cancer treatment, and the loss of effective antibiotics would make these procedures much more risky. In addition, the development of new antibiotics is slow, and there is growing concerns that we will reach a point where no effective antibiotics are available to treat infections.To mitigate the impact of antibiotic resistance on microbial pathogenesis, it is essential to reduce the overuse and misuse of antibiotics. This can be done by improving the prescribing practices of healthcare providers, reducing the unnecessary use of antibiotics, and promoting the use of alternative treatments, such as vaccines and other non-antibiotic therapies. In addition, there is a need for increased investment in the development of new antibiotics and the improvement of existing ones. This can be done through public-private partnerships, research and development funding, and the creation of incentives for the development of new antibiotics. Finally, it is important to educate the public about the impact of antibiotic resistance and the importance of responsible use of antibiotics. This can be done through public health campaigns, educational programs in schools, and outreach efforts to healthcare providers and patients .
The impact of antibiotic resistance on microbial pathogenesis is significant and far-reaching. The increasing prevalence of antibiotic-resistant strains of bacteria is making it more difficult to treat infections and has serious implications for public health and the future of medicine. To address this issue, it is essential to reduce the overuse and misuse of antibiotics, invest in the development of new antibiotics, and educate the public about the importance of responsible use of antibiotics. Only by taking a comprehensive and collaborative approach to this issue can we effectively mitigate the impact of antibiotic resistance on microbial pathogenesis and protect public health .
- Tong SY, Davis JS, Eichenberger E, et al. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 2015;28(3):603-61.
- Lakhundi S, Zhang K. Methicillin-resistant Staphylococcus aureus: molecular characterization, evolution, and epidemiology. Clin Microbiol Rev. 2018;31(4):e00020-18.
- Choi YJ, Thines M. Host jumps and radiation, not co‐divergence drives diversification of obligate pathogens. A case study in downy mildews and Asteraceae. PloS one. 2015;10(7):e0133655.
- Colla G, Rouphael Y, Di Mattia E, et al. Co‐inoculation of Glomus intraradices and Trichoderma atroviride acts as a biostimulant to promote growth, yield and nutrient uptake of vegetable crops. J Sci Food Agric. 2015;95(8):1706-15.
- Yu D, Wang J, Shao X, et al. Antifungal modes of action of tea tree oil and its two characteristic components against Botrytis cinerea. J Appl Microbiol. 2015;119(5):1253-62.