Case Reports in Surgery and Invasive Procedures

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (202) 780-3397

Short Communication - Case Reports in Surgery and Invasive Procedures (2023) Volume 7, Issue 4

Surgical Intervention in Recurrent Pseudomembranous Colitis

Chen Syu*

Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan

*Corresponding Author:
Chen Syu
Department of Internal Medicine,
Kaohsiung Medical University,
Kaohsiung City, Taiwan

Received: 27-Jun-2023, Manuscript No. AACRSIP-23-104891; Editor assigned: 29-Jun-2023, PreQC No. AACRSIP-23-104891(PQ); Reviewed: 13-Jul-2023, QC No. AACRSIP-23-104891; Revised: 17-Jul-2023, Manuscript No. AACRSIP-23-104891; Published: 24-Jul-2023, DOI:10.35841/aacrsip-7.4.156

Citation: Syu C. Surgical intervention in recurrent pseudomembranous colitis. Case Rep Surg Invasive Proced. 2023;7(4):156

Visit for more related articles at Case Reports in Surgery and Invasive Procedures




Recurrent pseudomembranous colitis (PMC) poses a significant clinical challenge, requiring prompt and effective management to mitigate morbidity and improve patient outcomes. While antibiotic therapy remains the primary treatment for initial episodes of PMC, surgical intervention becomes a critical consideration in cases of recurrent or refractory disease. Current strategies and outcomes associated with surgical intervention in recurrent pseudomembranous colitis, shedding light on the indications, surgical options, and postoperative considerations [1].

Recurrent pseudomembranous colitis presents a complex scenario where the efficacy of conservative management strategies declines. The role of surgical intervention as a therapeutic option for patients with recurrent PMC, examining the factors contributing to recurrence and the challenges associated with surgical decision-making. A comprehensive understanding of the pathophysiology and risk factors associated with recurrent PMC is crucial for identifying patients who are at increased risk. This section explores the microbial dysbiosis, toxin production, and other predisposing factors contributing to recurrent disease [2].

The decision to pursue surgical intervention in recurrent PMC requires a careful assessment of clinical parameters and failed medical therapy. This section outlines the indications for surgical management, including severe disease refractory to antibiotics, toxic megacolon, complications like perforation, and recurrent disease despite adequate medical therapy. Various surgical options exist for managing recurrent PMC, ranging from limited resections to total colectomy with or without ileostomy. This section discusses the pros and cons of each approach, highlighting factors influencing the choice of surgical procedure, such as disease severity, patient comorbidities, and surgical expertise [3].

Understanding the outcomes and potential complications associated with surgical intervention is crucial for patient counseling and decision-making. This section provides an overview of postoperative outcomes, including morbidity, mortality, recurrence rates, functional outcomes, and quality of life following surgery. Recent advancements in surgical techniques have expanded the armamentarium for managing recurrent PMC. This section highlights emerging approaches such as fecal microbiota transplantation, minimally invasive surgery, and immunomodulatory therapies, discussing their potential role in recurrent PMC management. Postoperative care and surveillance play a vital role in optimizing patient outcomes after surgical intervention for recurrent PMC. This section covers postoperative care protocols, monitoring for disease recurrence, and long-term management strategies to minimize the risk of relapse [4,5].

Recurrent pseudomembranous colitis presents a complex clinical scenario requiring a multidisciplinary approach. Surgical intervention is a valuable tool in the management of recurrent PMC when medical therapy fails. Understanding the indications, surgical options, outcomes, and complications associated with surgical intervention is crucial for providing optimal care to patients with recurrent PMC. Further research and collaboration are needed to refine surgical strategies and improve patient outcomes in this challenging condition.




  1. Ali SO, Welch JP, Dring RJ. Early surgical intervention for fulminant pseudomembranous colitis. Am Surg. 2008;74(1):20-6.

    Indexed at, Google Scholar, Cross Ref

  2. Surawicz C, McFarland L. Pseudomembranous colitis: Causes and cures. Digest. 1999;60(2):91-100. 

    Indexed at, Google Scholar, Cross Ref

  3. Gallegos-Orozco JF, Paskvan-Gawryletz CD, Gurudu SR, et al. Successful colonoscopic fecal transplant for severe acute Clostridium difficile pseudomembranous colitis. Rev Gastroenterol Mex. 2012;77(1):40-2.

    Indexed at, Google Scholar

  4. Sheikh RA, Yasmeen S, Pauly MP, et al. Pseudomembranous colitis without diarrhea presenting clinically as acute intestinal pseudo-obstruction. J Gastroenterol. 2001;36(9).

    Indexed at, Google Scholar, Cross Ref

  5. Kappas A, Shinagawa N, Arabi Y, et al. Diagnosis of pseudomembranous colitis. Br Med J. 1978;1(6114):675-8.

    Indexed at, Google Scholar, Cross Ref

Get the App